Progress toward allosteric ligands of metabotropic glutamate 7 (mGlu7) receptor: 2008–present

le Vázquez-Villa, Henar, Trabanco, Andrés A.
Foilsithe in Medchemcomm (2018)

Identification of Allosteric Modulators of Metabotropic Glutamate 7 Receptor Using Proteochemometric Modeling

le Tresadern, Gary, Trabanco, Andres A., Pérez-Benito, Laura, Overington, John P., van Vlijmen, Herman W. T., van Westen, Gerard J. P.
Foilsithe in J Chem Inf Model (2017)

Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation

le Hell, Sandrine M., Meyer, Claudio F., Misale, Antonio, Sap, Jeroen B. I., Christensen, Kirsten E., Willis, Michael C., Trabanco, Andrés A., Gouverneur, Véronique
Foilsithe in Angew Chem Int Ed Engl (2020)

Pharmacological and pharmacokinetic properties of JNJ-40411813, a positive allosteric modulator of the mGlu2 receptor

le Lavreysen, Hilde, Ahnaou, Abdellah, Drinkenburg, Wilhelmus, Langlois, Xavier, Mackie, Claire, Pype, Stefan, Lütjens, Robert, Le Poul, Emmanuel, Trabanco, Andrés A, Nuñez, José María Cid
Foilsithe in Pharmacol Res Perspect (2015)

Pyrido[4,3-e][1,2,4]triazolo[4,3-a]pyrazines as Selective, Brain Penetrant Phosphodiesterase 2 (PDE2) Inhibitors

le Rombouts, Frederik J. R., Tresadern, Gary, Buijnsters, Peter, Langlois, Xavier, Tovar, Fulgencio, Steinbrecher, Thomas B., Vanhoof, Greet, Somers, Marijke, Andrés, José-Ignacio, Trabanco, Andrés A.
Foilsithe in ACS Med Chem Lett (2015)

Spiro-oxindole Piperidines and 3-(Azetidin-3-yl)-1H-benzimidazol-2-ones as mGlu(2) Receptor PAMs

le de Lucas, Ana Isabel, Vega, Juan Antonio, Matesanz, Encarnación, Linares, María Lourdes, García Molina, Aránzazu, Tresadern, Gary, Lavreysen, Hilde, Trabanco, Andrés A., Cid, José María
Foilsithe in ACS Med Chem Lett (2019)

Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ‐46281222

le Doornbos, Maarten L J, Pérez‐Benito, Laura, Tresadern, Gary, Mulder‐Krieger, Thea, Biesmans, Ilse, Trabanco, Andrés A, Cid, Jose María, Lavreysen, Hilde, IJzerman, Adriaan P, Heitman, Laura H
Foilsithe in Br J Pharmacol (2016)

Structure-Based Design of a Potent, Selective, and Brain Penetrating PDE2 Inhibitor with Demonstrated Target Engagement

le Buijnsters, Peter, De Angelis, Meri, Langlois, Xavier, Rombouts, Frederik J. R., Sanderson, Wendy, Tresadern, Gary, Ritchie, Alison, Trabanco, Andrés A., VanHoof, Greet, Roosbroeck, Yves Van, Andrés, José-Ignacio
Foilsithe 2014

Covalent Allosteric Probe for the Metabotropic Glutamate Receptor 2: Design, Synthesis, and Pharmacological Characterization

le Doornbos, Maarten L. J., Wang, Xuesong, Vermond, Sophie C., Peeters, Luc, Pérez-Benito, Laura, Trabanco, Andrés A., Lavreysen, Hilde, Cid, José María, Heitman, Laura H., Tresadern, Gary, IJzerman, Adriaan P.
Foilsithe in J Med Chem (2018)

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

le Sap, Jeroen B. I., Straathof, Natan J. W., Knauber, Thomas, Meyer, Claudio F., Médebielle, Maurice, Buglioni, Laura, Genicot, Christophe, Trabanco, Andrés A., Noël, Timothy, am Ende, Christopher W., Gouverneur, Véronique
Foilsithe in J Am Chem Soc (2020)

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

le Roagna, Giulia, Ascough, David M. H., Ibba, Francesco, Vicini, Anna Chiara, Fontana, Alberto, Christensen, Kirsten E., Peschiulli, Aldo, Oehlrich, Daniel, Misale, Antonio, Trabanco, Andrés A., Paton, Robert S., Pupo, Gabriele, Gouverneur, Véronique
Foilsithe in J Am Chem Soc (2020)

Fragment Binding to β-Secretase 1 without Catalytic Aspartate Interactions Identified via Orthogonal Screening Approaches

le Rombouts, Frederik J. R., Alexander, Richard, Cleiren, Erna, De Groot, Alex, Carpentier, Michel, Dijkmans, Joyce, Fierens, Katleen, Masure, Stefan, Moechars, Diederik, Palomino-Schätzlein, Martina, Pineda-Lucena, Antonio, Trabanco, Andrés A., Van Glabbeek, Daan, Vos, Ann, Tresadern, Gary
Foilsithe in ACS Omega (2017)

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis

le Miles, Luke A., Hermans, Stefan J., Crespi, Gabriela A.N., Gooi, Jonathan H., Doughty, Larissa, Nero, Tracy L., Markulić, Jasmina, Ebneth, Andreas, Wroblowski, Berthold, Oehlrich, Daniel, Trabanco, Andrés A., Rives, Marie-Laure, Royaux, Ines, Hancock, Nancy C., Parker, Michael W.
Foilsithe in iScience (2019)

Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads

le Oehlrich, Daniel, Peschiulli, Aldo, Tresadern, Gary, Van Gool, Michiel, Vega, Juan Antonio, De Lucas, Ana Isabel, Alonso de Diego, Sergio A., Prokopcova, Hana, Austin, Nigel, Van Brandt, Sven, Surkyn, Michel, De Cleyn, Michel, Vos, Ann, Rombouts, Frederik J. R., Macdonald, Gregor, Moechars, Dieder, Gijsen, Harrie J. M., Trabanco, Andrés A.
Foilsithe in ACS Med Chem Lett (2019)

Dihydrothiazolopyridone Derivatives as a Novel Family of Positive Allosteric Modulators of the Metabotropic Glutamate 5 (mGlu(5)) Receptor

le Bartolomé-Nebreda, José Manuel, Conde-Ceide, Susana, Delgado, Francisca, Iturrino, Laura, Pastor, Joaquín, Pena, Miguel Ángel, Trabanco, Andrés A., Tresadern, Gary, Wassvik, Carola M., Stauffer, Shaun R., Jadhav, Satyawan, Gogi, Kiran, Vinson, Paige N., Noetzel, Meredith J., Days, Emily, Weaver, C. David, Lindsley, Craig W., Niswender, Colleen M., Jones, Carrie K., Conn, P. Jeffrey, Rombouts, Frederik, Lavreysen, Hilde, Macdonald, Gregor J., Mackie, Claire, Steckler, Thomas
Foilsithe 2013

Discovery of 1,5-Disubstituted Pyridones: A New Class of Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

le Cid, Jose María, Duvey, Guillaume, Cluzeau, Philippe, Nhem, Vanthea, Macary, Karim, Raux, Alexandre, Poirier, Nicolas, Muller, Jessica, Boléa, Christelle, Finn, Terry, Poli, Sonia, Epping-Jordan, Mark, Chamelot, Emilie, Derouet, Francis, Girard, Francoise, Macdonald, Gregor J., Vega, Juan Antonio, de Lucas, Ana Isabel, Matesanz, Encarnación, Lavreysen, Hilde, Linares, María Lourdes, Oehlrich, Daniel, Oyarzábal, Julen, Tresadern, Gary, Trabanco, Andrés A., Andrés, Jose Ignacio, Le Poul, Emmanuel, Imogai, Hassan, Lutjens, Robert, Rocher, Jean-Philippe
Foilsithe 2010