Pharmacological and pharmacokinetic properties of JNJ-40411813, a positive allosteric modulator of the mGlu2 receptor

Compounds modulating metabotropic glutamate type 2 (mGlu2) receptor activity may have therapeutic benefits in treating psychiatric disorders like schizophrenia and anxiety. The pharmacological and pharmacokinetic properties of a novel mGlu2 receptor-positive allosteric modulator (PAM), 1-butyl-3-chl...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Lavreysen, Hilde, Ahnaou, Abdellah, Drinkenburg, Wilhelmus, Langlois, Xavier, Mackie, Claire, Pype, Stefan, Lütjens, Robert, Le Poul, Emmanuel, Trabanco, Andrés A, Nuñez, José María Cid
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317228/
https://ncbi.nlm.nih.gov/pubmed/25692015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.96
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