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Modulation of mGlu2 Receptors, but Not PDE10A Inhibition Normalizes Pharmacologically-Induced Deviance in Auditory Evoked Potentials and Oscillations in Conscious Rats

Improvement of cognitive impairments represents a high medical need in the development of new antipsychotics. Aberrant EEG gamma oscillations and reductions in the P1/N1 complex peak amplitude of the auditory evoked potential (AEP) are neurophysiological biomarkers for schizophrenia that indicate di...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ahnaou, Abdallah, Biermans, Ria, Drinkenburg, Wilhelmus H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726622/
https://ncbi.nlm.nih.gov/pubmed/26808689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147365
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