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Modulation of mGlu2 Receptors, but Not PDE10A Inhibition Normalizes Pharmacologically-Induced Deviance in Auditory Evoked Potentials and Oscillations in Conscious Rats

Improvement of cognitive impairments represents a high medical need in the development of new antipsychotics. Aberrant EEG gamma oscillations and reductions in the P1/N1 complex peak amplitude of the auditory evoked potential (AEP) are neurophysiological biomarkers for schizophrenia that indicate di...

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Vydáno v:PLoS One
Hlavní autoři: Ahnaou, Abdallah, Biermans, Ria, Drinkenburg, Wilhelmus H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726622/
https://ncbi.nlm.nih.gov/pubmed/26808689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147365
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