Coupling of the human A(1) adenosine receptor to different heterotrimeric G proteins: evidence for agonist-specific G protein activation

nork Cordeaux, Yolande, IJzerman, Adriaan P, Hill, Stephen J
Argitaratua 2004

The Added Value of Assessing Ligand–Receptor Binding Kinetics in Drug Discovery

nork Guo, Dong, Heitman, Laura H., IJzerman, Adriaan P.
Argitaratua izan da ACS Med Chem Lett (2016)

Label-free detection of transporter activity via GPCR signalling in living cells: A case for SLC29A1, the equilibrative nucleoside transporter 1

nork Vlachodimou, Anna, IJzerman, Adriaan P., Heitman, Laura H.
Argitaratua izan da Sci Rep (2019)

Allosteric modulation of G protein‐coupled receptors by amiloride and its derivatives. Perspectives for drug discovery?

nork Massink, Arnault, Amelia, Tasia, Karamychev, Alex, IJzerman, Adriaan P.
Argitaratua izan da Med Res Rev (2019)

Medicinal Chemistry of P2 and Adenosine Receptors: Common Scaffolds Adapted for Multiple Targets

nork Jacobson, Kenneth A., IJzerman, Adriaan P., Müller, Christa E.
Argitaratua izan da Biochem Pharmacol (2020)

Allosteric Modulation of Purine and Pyrimidine Receptors

nork Jacobson, Kenneth A., Gao, Zhan-Guo, Göblyös, Anikó, IJzerman, Adriaan P.
Argitaratua 2011

Functional efficacy of adenosine A(2A) receptor agonists is positively correlated to their receptor residence time

nork Guo, Dong, Mulder-Krieger, Thea, IJzerman, Adriaan P, Heitman, Laura H
Argitaratua 2012

Allosteric Modulation of the Adenosine Family of Receptors

nork Gao, Zhan-Guo, Kim, Soo-Kyung, IJzerman, Adriaan P., Jacobson, Kenneth A.
Argitaratua 2005

Molecular probes for the human adenosine receptors

nork Yang, Xue, Heitman, Laura H., IJzerman, Adriaan P., van der Es, Daan
Argitaratua izan da Purinergic Signal (2020)

Internalization and desensitization of adenosine receptors

nork Klaasse, Elisabeth C., IJzerman, Adriaan P., de Grip, Willem J., Beukers, Margot W.
Argitaratua 2007

Flexible modulation of agonist efficacy at the human A(3 )adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000

nork Gao, Zhan-Guo, Ye, Kai, Göblyös, Anikó, IJzerman, Adriaan P, Jacobson, Kenneth A
Argitaratua 2008

G Protein-Coupled Receptor Heteromerization: A Role in Allosteric Modulation of Ligand Binding

nork Gomes, Ivone, IJzerman, Adriaan P., Ye, Kai, Maillet, Emeline L., Devi, Lakshmi A.
Argitaratua 2011

Proteochemometric modelling coupled to in silico target prediction: an integrated approach for the simultaneous prediction of polypharmacology and binding affinity/potency of small...

nork Paricharak, Shardul, Cortés-Ciriano, Isidro, IJzerman, Adriaan P, Malliavin, Thérèse E, Bender, Andreas
Argitaratua izan da J Cheminform (2015)

Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the β(2)-adrenergic receptor

nork Carmine, Renata Del, Ambrosio, Caterina, Sbraccia, Maria, Cotecchia, Susanna, Ijzerman, Adriaan P, Costa, Tommaso
Argitaratua 2002

Novel 2- and 4- Substituted 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as Allosteric Modulators of the A(3) Adenosine Receptor

nork Kim, Yoonkyung, de Castro, Sonia, Gao, Zhan-Guo, IJzerman, Adriaan P., Jacobson, Kenneth A.
Argitaratua 2009

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update

nork Fredholm, Bertil B., IJzerman, Adriaan P., Jacobson, Kenneth A., Linden, Joel, Müller, Christa E.
Argitaratua 2011

Quantitative prediction of selectivity between the A(1) and A(2A) adenosine receptors

nork Burggraaff, Lindsey, van Vlijmen, Herman W. T., IJzerman, Adriaan P., van Westen, Gerard J. P.
Argitaratua izan da J Cheminform (2020)

A(3) Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action

nork Cohen, Shira, Barer, Faina, Bar-Yehuda, Sara, IJzerman, Adriaan P., Jacobson, Kenneth A., Fishman, Pnina
Argitaratua 2014

Hemodynamic effects and histamine release elicited by the selective adenosine A(3) receptor agonist 2-Cl-IB-MECA in conscious rats

nork Van Schaick, Erno A., Jacobson, Kenneth A., Kim, Hea O., IJzerman, Adriaan P., Danhof, Meindert
Argitaratua izan da Eur J Pharmacol (1996)

An exploration strategy improves the diversity of de novo ligands using deep reinforcement learning: a case for the adenosine A(2A) receptor

nork Liu, Xuhan, Ye, Kai, van Vlijmen, Herman W. T., IJzerman, Adriaan P., van Westen, Gerard J. P.
Argitaratua izan da J Cheminform (2019)