Allosteric modulation of G protein‐coupled receptors by amiloride and its derivatives. Perspectives for drug discovery?

Por Massink, Arnault, Amelia, Tasia, Karamychev, Alex, IJzerman, Adriaan P.
Publicado no Med Res Rev (2019)

In search of novel ligands using a structure-based approach: a case study on the adenosine A(2A) receptor

Por Lenselink, Eelke B., Beuming, Thijs, van Veen, Corine, Massink, Arnault, Sherman, Woody, van Vlijmen, Herman W. T., IJzerman, Adriaan P.
Publicado no J Comput Aided Mol Des (2016)

Molecular mechanism of allosteric modulation at GPCRs: insight from a binding kinetics study at the human A(1) adenosine receptor

Por Guo, Dong, Venhorst, Suzanne N, Massink, Arnault, van Veldhoven, Jacobus P D, Vauquelin, Georges, IJzerman, Adriaan P, Heitman, Laura H
Publicado no Br J Pharmacol (2014)

Sodium Ion Binding Pocket Mutations and Adenosine A(2A) Receptor Function

Por Massink, Arnault, Gutiérrez-de-Terán, Hugo, Lenselink, Eelke B., Ortiz Zacarías, Natalia V., Xia, Lizi, Heitman, Laura H., Katritch, Vsevolod, Stevens, Raymond C., IJzerman, Adriaan P.
Publicado no Mol Pharmacol (2015)

The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor

Por Gutiérrez-de-Terán, Hugo, Massink, Arnault, Rodríguez, David, Liu, Wei, Han, Gye Won, Joseph, Jeremiah S., Katritch, Ilia, Heitman, Laura H., Xia, Lizi, IJzerman, Adriaan P., Cherezov, Vadim, Katritch, Vsevolod, Stevens, Raymond C.
Publicado em 2013