Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation

Por Miles, Luke A., Crespi, Gabriela A. N., Doughty, Larissa, Parker, Michael W.
Publicado em 2013

ERRATUM: Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation

Por Miles, Luke A., Crespi, Gabriela A. N., Doughty, Larissa, Parker, Michael W.
Publicado em 2013

Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer’s disease immunotherapy candidate bapineuzumab complexed with amyloid-β

Por Crespi, Gabriela A. N., Ascher, David B., Parker, Michael W., Miles, Luke A.
Publicado em 2014

Molecular basis for mid-region amyloid-β capture by leading Alzheimer's disease immunotherapies

Por Crespi, Gabriela A. N., Hermans, Stefan J., Parker, Michael W., Miles, Luke A.
Publicado no Sci Rep (2015)

Ex vivo(18)O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway

Por Portelius, Erik, Mattsson, Niklas, Pannee, Josef, Zetterberg, Henrik, Gisslén, Magnus, Vanderstichele, Hugo, Gkanatsiou, Eleni, Crespi, Gabriela A. N., Parker, Michael W., Miles, Luke A., Gobom, Johan, Blennow, Kaj
Publicado no Mol Neurodegener (2017)

Copper binding to the Alzheimer’s disease amyloid precursor protein

Por Kong, Geoffrey K.-W., Miles, Luke A., Crespi, Gabriela A. N., Morton, Craig J., Ng, Hooi Ling, Barnham, Kevin J., McKinstry, William J., Cappai, Roberto, Parker, Michael W.
Publicado em 2007

Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Aβ peptides associated with Alzheimer’s disease

Por Wun, Kwok S., Miles, Luke A., Crespi, Gabriela A. N., Wycherley, Kaye, Ascher, David B., Barnham, Kevin J., Cappai, Roberto, Beyreuther, Konrad, Masters, Colin L., Parker, Michael W., McKinstry, William J.
Publicado em 2008

Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability

Por Gillinder, Kevin R., Ilsley, Melissa D., Nébor, Danitza, Sachidanandam, Ravi, Lajoie, Mathieu, Magor, Graham W., Tallack, Michael R., Bailey, Timothy, Landsberg, Michael J., Mackay, Joel P., Parker, Michael W., Miles, Luke A., Graber, Joel H., Peters, Luanne L., Bieker, James J., Perkins, Andrew C.
Publicado no Nucleic Acids Res (2017)

Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites

Por Braig, David, Nero, Tracy L., Koch, Hans-Georg, Kaiser, Benedict, Wang, Xiaowei, Thiele, Jan R., Morton, Craig J., Zeller, Johannes, Kiefer, Jurij, Potempa, Lawrence A., Mellett, Natalie A., Miles, Luke A., Du, Xiao-Jun, Meikle, Peter J., Huber-Lang, Markus, Stark, G. Björn, Parker, Michael W., Peter, Karlheinz, Eisenhardt, Steffen U.
Publicado no Nat Commun (2017)