Copper binding to the Alzheimer’s disease amyloid precursor protein

Alzheimer’s disease is the fourth biggest killer in developed countries. Amyloid precursor protein (APP) plays a central role in the development of the disease, through the generation of a peptide called Aβ by proteolysis of the precursor protein. APP can function as a metalloprotein and modulate co...

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Detalhes bibliográficos
Main Authors: Kong, Geoffrey K.-W., Miles, Luke A., Crespi, Gabriela A. N., Morton, Craig J., Ng, Hooi Ling, Barnham, Kevin J., McKinstry, William J., Cappai, Roberto, Parker, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921068/
https://ncbi.nlm.nih.gov/pubmed/18030462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-007-0234-3
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