Prevention of breast cancer by recapitulation of pregnancy hormone levels

著者: Tonetti, Debra A
出版事項 2004

Estradiol-Induced Regression in T47D:A18/PKCα Tumors Requires the Estrogen Receptor And Interaction with the Extracellular Matrix

著者: Zhang, Yiyun, Zhao, Huiping, Asztalos, Szilard, Chisamore, Michael, Sitabkhan, Yasmin, Tonetti, Debra A.
出版事項 2009

PKCα and ERβ Are Associated with Triple-Negative Breast Cancers in African American and Caucasian Patients

著者: Tonetti, Debra A., Gao, Weihua, Escarzaga, Diana, Walters, Kelly, Szafran, April, Coon, John S.
出版事項 2012

Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer

著者: Perez White, Bethany, Molloy, Mary Ellen, Zhao, Huiping, Zhang, Yiyun, Tonetti, Debra A
出版事項 2013

Retraction Note to: Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer

著者: White, Bethany Perez, Molloy, Mary Ellen, Zhao, Huiping, Zhang, Yiyun, Tonetti, Debra A.
出版年 Mol Cancer (2017)

Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin

著者: Pham, Thao N. D., Perez White, Bethany E., Zhao, Huiping, Mortazavi, Fariborz, Tonetti, Debra A.
出版年 BMC Cancer (2017)

Novel Selective Estrogen Receptor Downregulators (SERDs) Developed Against Treatment-Resistant Breast Cancer

著者: Xiong, Rui, Zhao, Jiong, Gutgesell, Lauren M., Wang, Yueting, Lee, Sue, Karumudi, Bhargava, Zhao, Huiping, Lu, Yunlong, Tonetti, Debra A., Thatcher, Gregory R. J.
出版年 J Med Chem (2017)

Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer

著者: Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Hanspal, Jay S., Fan, Ping, Xiong, Rui, Tonetti, Debra A., Thatcher, Gregory R.J., Jordan, V. Craig
出版年 Mol Pharmacol (2020)

Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation

著者: Rauscher, Garth H., Kresovich, Jacob K., Poulin, Matthew, Yan, Liying, Macias, Virgilia, Mahmoud, Abeer M., Al-Alem, Umaima, Kajdacsy-Balla, Andre, Wiley, Elizabeth L., Tonetti, Debra, Ehrlich, Melanie
出版年 BMC Cancer (2015)

Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbocicl...

著者: Li, Yangfeng, Zhao, Jiong, Gutgesell, Lauren M., Shen, Zhengnan, Ratia, Kiira, Dye, Katherine, Dubrovskyi, Oleksii, Zhao, Huiping, Huang, Fei, Tonetti, Debra A., Thatcher, Gregory R. J., Xiong, Rui
出版年 J Med Chem (2020)

Click synthesis of estradiol–cyclodextrin conjugates as cell compartment selective estrogens

著者: Kim, Hye-Yeong, Sohn, Johann, Wijewickrama, Gihani T., Edirisinghe, Praneeth, Gherezghiher, Teshome, Hemachandra, Madhubani, Lu, Pei-Yi, Chandrasena, R. Esala, Molloy, Mary Ellen, Tonetti, Debra A., Thatcher, Gregory R. J.
出版事項 2009

Novel Selective Estrogen Mimics for the Treatment of Tamoxifen-Resistant Breast Cancer

著者: Molloy, Mary Ellen, Perez White, Bethany E., Gherezghiher, Teshome, Michalsen, Bradley T., Xiong, Rui, Patel, Hitisha, Zhao, Huiping, Maximov, Philipp Y., Jordan, V. Craig, Thatcher, Gregory R. J., Tonetti, Debra A.
出版年 Mol Cancer Ther (2014)

PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer

著者: Zheng, Yu, Wang, Zebin, Bie, Wenjun, Brauer, Patrick M., White, Bethany E. Perez, Li, Jing, Nogueira, Veronique, Raychaudhuri, Pradip, Hay, Nissim, Tonetti, Debra A., Macias, Virgilia, Kajdacsy-Balla, André, Tyner, Angela L.
出版事項 2013

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors

著者: Peng, Maoyu, Emmadi, Rajyasree, Wang, Zebin, Wiley, Elizabeth L., Gann, Peter H., Khan, Seema A., Banerji, Nilanjana, McDonald, William, Asztalos, Szilard, Pham, Thao N.D., Tonetti, Debra A., Tyner, Angela L.
出版事項 2014

High incidence of triple negative breast cancers following pregnancy and an associated gene expression signature

著者: Asztalos, Szilard, Pham, Thao N., Gann, Peter H., Hayes, Meghan K., Deaton, Ryan, Wiley, Elizabeth L., Emmadi, Rajyasree, Kajdacsy-Balla, Andre, Banerji, Nilanjana, McDonald, William, Khan, Seema A., Tonetti, Debra A.
出版年 Springerplus (2015)

Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution

著者: Stanford, Jamie C., Young, Christian, Hicks, Donna, Owens, Philip, Williams, Andrew, Vaught, David B., Morrison, Meghan M., Lim, Jiyeon, Williams, Michelle, Brantley-Sieders, Dana M., Balko, Justin M., Tonetti, Debra, Earp, H. Shelton, Cook, Rebecca S.
出版年 J Clin Invest (2014)

Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer

著者: Xiong, Rui, Patel, Hitisha K., Gutgesell, Lauren M., Zhao, Jiong, Delgado-Rivera, Loruhama, Pham, Thao N.D., Zhao, Huiping, Carlson, Kathryn, Martin, Teresa, Katzenellenbogen, John A., Moore, Terry W., Tonetti, Debra A., Thatcher, Gregory R. J.
出版年 J Med Chem (2015)

Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer

著者: Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Fanning, Sean W., Hanspal, Jay S., Fan, Ping, Foulds, Charles E., Chen, Yue, Malovannaya, Anna, Jain, Antrix, Xiong, Rui, Greene, Geoffrey L., Tonetti, Debra A., Thatcher, Gregory R. J., Jordan, V. Craig
出版年 Mol Cancer Ther (2020)

Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer

著者: Lu, Yunlong, Gutgesell, Lauren M., Xiong, Rui, Zhao, Jiong, Li, Yangfeng, Rosales, Carlo I., Hollas, Michael, Shen, Zhengnan, Gordon-Blake, Jesse, Dye, Katherine, Wang, Yueting, Lee, Sue, Chen, Hu, He, Donghong, Dubrovyskyii, Oleksii, Zhao, Huiping, Huang, Fei, Lasek, Amy W., Tonetti, Debra A., Thatcher, Gregory R. J.
出版年 J Med Chem (2019)

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

著者: Andreano, Kaitlyn J., Wardell, Suzanne E., Baker, Jennifer G., Desautels, Taylor K., Baldi, Robert, Chao, Christina A., Heetderks, Kendall A., Bae, Yeeun, Xiong, Rui, Tonetti, Debra A., Gutgesell, Lauren M., Zhao, Jiong, Sorrentino, Jessica A., Thompson, Delita A., Bisi, John E., Strum, Jay C., Thatcher, Gregory R. J., Norris, John D.
出版年 Breast Cancer Res Treat (2020)