Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer

Almost 70% of breast cancers are estrogen receptor α (ERα) positive. Tamoxifen, a selective estrogen receptor modulator (SERM), represents the standard of care for many patients; however, 30-50% develop resistance, underlining the need for alternative therapeutics. Paradoxically, agonists at ERα suc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Xiong, Rui, Patel, Hitisha K., Gutgesell, Lauren M., Zhao, Jiong, Delgado-Rivera, Loruhama, Pham, Thao N.D., Zhao, Huiping, Carlson, Kathryn, Martin, Teresa, Katzenellenbogen, John A., Moore, Terry W., Tonetti, Debra A., Thatcher, Gregory R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779956/
https://ncbi.nlm.nih.gov/pubmed/26681208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01276
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados