Click synthesis of estradiol–cyclodextrin conjugates as cell compartment selective estrogens

Cyclodextrin (CD) is a well known drug carrier and excipient for enhancing aqueous solubility. CDs themselves are anticipated to have low membrane permeability because of relatively high hydrophilicity and molecular weight. CD derivatization with 17-beta estradiol (E(2)) was explored extensively usi...

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Detalhes bibliográficos
Main Authors: Kim, Hye-Yeong, Sohn, Johann, Wijewickrama, Gihani T., Edirisinghe, Praneeth, Gherezghiher, Teshome, Hemachandra, Madhubani, Lu, Pei-Yi, Chandrasena, R. Esala, Molloy, Mary Ellen, Tonetti, Debra A., Thatcher, Gregory R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906776/
https://ncbi.nlm.nih.gov/pubmed/20031420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.11.046
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