Prevention of breast cancer by recapitulation of pregnancy hormone levels

Por Tonetti, Debra A
Publicado em 2004

Estradiol-Induced Regression in T47D:A18/PKCα Tumors Requires the Estrogen Receptor And Interaction with the Extracellular Matrix

Por Zhang, Yiyun, Zhao, Huiping, Asztalos, Szilard, Chisamore, Michael, Sitabkhan, Yasmin, Tonetti, Debra A.
Publicado em 2009

PKCα and ERβ Are Associated with Triple-Negative Breast Cancers in African American and Caucasian Patients

Por Tonetti, Debra A., Gao, Weihua, Escarzaga, Diana, Walters, Kelly, Szafran, April, Coon, John S.
Publicado em 2012

Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer

Por Perez White, Bethany, Molloy, Mary Ellen, Zhao, Huiping, Zhang, Yiyun, Tonetti, Debra A
Publicado em 2013

Retraction Note to: Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer

Por White, Bethany Perez, Molloy, Mary Ellen, Zhao, Huiping, Zhang, Yiyun, Tonetti, Debra A.
Publicado no Mol Cancer (2017)

Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin

Por Pham, Thao N. D., Perez White, Bethany E., Zhao, Huiping, Mortazavi, Fariborz, Tonetti, Debra A.
Publicado no BMC Cancer (2017)

Novel Selective Estrogen Receptor Downregulators (SERDs) Developed Against Treatment-Resistant Breast Cancer

Por Xiong, Rui, Zhao, Jiong, Gutgesell, Lauren M., Wang, Yueting, Lee, Sue, Karumudi, Bhargava, Zhao, Huiping, Lu, Yunlong, Tonetti, Debra A., Thatcher, Gregory R. J.
Publicado no J Med Chem (2017)

Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer

Por Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Hanspal, Jay S., Fan, Ping, Xiong, Rui, Tonetti, Debra A., Thatcher, Gregory R.J., Jordan, V. Craig
Publicado no Mol Pharmacol (2020)

Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation

Por Rauscher, Garth H., Kresovich, Jacob K., Poulin, Matthew, Yan, Liying, Macias, Virgilia, Mahmoud, Abeer M., Al-Alem, Umaima, Kajdacsy-Balla, Andre, Wiley, Elizabeth L., Tonetti, Debra, Ehrlich, Melanie
Publicado no BMC Cancer (2015)

Click synthesis of estradiol–cyclodextrin conjugates as cell compartment selective estrogens

Por Kim, Hye-Yeong, Sohn, Johann, Wijewickrama, Gihani T., Edirisinghe, Praneeth, Gherezghiher, Teshome, Hemachandra, Madhubani, Lu, Pei-Yi, Chandrasena, R. Esala, Molloy, Mary Ellen, Tonetti, Debra A., Thatcher, Gregory R. J.
Publicado em 2009

Novel Selective Estrogen Mimics for the Treatment of Tamoxifen-Resistant Breast Cancer

Por Molloy, Mary Ellen, Perez White, Bethany E., Gherezghiher, Teshome, Michalsen, Bradley T., Xiong, Rui, Patel, Hitisha, Zhao, Huiping, Maximov, Philipp Y., Jordan, V. Craig, Thatcher, Gregory R. J., Tonetti, Debra A.
Publicado no Mol Cancer Ther (2014)

PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer

Por Zheng, Yu, Wang, Zebin, Bie, Wenjun, Brauer, Patrick M., White, Bethany E. Perez, Li, Jing, Nogueira, Veronique, Raychaudhuri, Pradip, Hay, Nissim, Tonetti, Debra A., Macias, Virgilia, Kajdacsy-Balla, André, Tyner, Angela L.
Publicado em 2013

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors

Por Peng, Maoyu, Emmadi, Rajyasree, Wang, Zebin, Wiley, Elizabeth L., Gann, Peter H., Khan, Seema A., Banerji, Nilanjana, McDonald, William, Asztalos, Szilard, Pham, Thao N.D., Tonetti, Debra A., Tyner, Angela L.
Publicado em 2014

High incidence of triple negative breast cancers following pregnancy and an associated gene expression signature

Por Asztalos, Szilard, Pham, Thao N., Gann, Peter H., Hayes, Meghan K., Deaton, Ryan, Wiley, Elizabeth L., Emmadi, Rajyasree, Kajdacsy-Balla, Andre, Banerji, Nilanjana, McDonald, William, Khan, Seema A., Tonetti, Debra A.
Publicado no Springerplus (2015)

Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution

Por Stanford, Jamie C., Young, Christian, Hicks, Donna, Owens, Philip, Williams, Andrew, Vaught, David B., Morrison, Meghan M., Lim, Jiyeon, Williams, Michelle, Brantley-Sieders, Dana M., Balko, Justin M., Tonetti, Debra, Earp, H. Shelton, Cook, Rebecca S.
Publicado no J Clin Invest (2014)

Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer

Por Xiong, Rui, Patel, Hitisha K., Gutgesell, Lauren M., Zhao, Jiong, Delgado-Rivera, Loruhama, Pham, Thao N.D., Zhao, Huiping, Carlson, Kathryn, Martin, Teresa, Katzenellenbogen, John A., Moore, Terry W., Tonetti, Debra A., Thatcher, Gregory R. J.
Publicado no J Med Chem (2015)

Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer

Por Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Fanning, Sean W., Hanspal, Jay S., Fan, Ping, Foulds, Charles E., Chen, Yue, Malovannaya, Anna, Jain, Antrix, Xiong, Rui, Greene, Geoffrey L., Tonetti, Debra A., Thatcher, Gregory R. J., Jordan, V. Craig
Publicado no Mol Cancer Ther (2020)

Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer

Por Lu, Yunlong, Gutgesell, Lauren M., Xiong, Rui, Zhao, Jiong, Li, Yangfeng, Rosales, Carlo I., Hollas, Michael, Shen, Zhengnan, Gordon-Blake, Jesse, Dye, Katherine, Wang, Yueting, Lee, Sue, Chen, Hu, He, Donghong, Dubrovyskyii, Oleksii, Zhao, Huiping, Huang, Fei, Lasek, Amy W., Tonetti, Debra A., Thatcher, Gregory R. J.
Publicado no J Med Chem (2019)

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

Por Andreano, Kaitlyn J., Wardell, Suzanne E., Baker, Jennifer G., Desautels, Taylor K., Baldi, Robert, Chao, Christina A., Heetderks, Kendall A., Bae, Yeeun, Xiong, Rui, Tonetti, Debra A., Gutgesell, Lauren M., Zhao, Jiong, Sorrentino, Jessica A., Thompson, Delita A., Bisi, John E., Strum, Jay C., Thatcher, Gregory R. J., Norris, John D.
Publicado no Breast Cancer Res Treat (2020)

Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

Por Rizzo, Paola, Miao, Haixi, D'Souza, Gwendolyn, Osipo, Clodia, Yun, Jieun, Zhao, Huiping, Mascarenhas, Joaquina, Wyatt, Debra, Antico, Giovanni, Hao, Lu, Yao, Katharine, Rajan, Prabha, Hicks, Chindo, Siziopikou, Kalliopi, Selvaggi, Suzanne, Bashir, Amina, Bhandari, Deepali, Marchese, Adriano, Lendahl, Urban, Qin, Jian-Zhong, Tonetti, Debra A., Albain, Kathy, Nickoloff, Brian J., Miele, Lucio
Publicado no Cancer Res (2008)