A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy

Por Patel, Hitisha K., Siklos, Marton I., Abdelkarim, Hazem, Mendonca, Emma L., Vaidya, Aditya, Petukhov, Pavel A., Thatcher, Gregory R. J.
Publicado em 2013

Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors

Por Patel, Hitisha K., Tao, Nianjun, Lee, Kyung-Min, Huerta, Mariela, Arlt, Heike, Mullarkey, Tara, Troy, Steven, Arteaga, Carlos L., Bihani, Teeru
Publicado no Breast Cancer Res (2019)

Novel Selective Estrogen Mimics for the Treatment of Tamoxifen-Resistant Breast Cancer

Por Molloy, Mary Ellen, Perez White, Bethany E., Gherezghiher, Teshome, Michalsen, Bradley T., Xiong, Rui, Patel, Hitisha, Zhao, Huiping, Maximov, Philipp Y., Jordan, V. Craig, Thatcher, Gregory R. J., Tonetti, Debra A.
Publicado no Mol Cancer Ther (2014)

Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer

Por Xiong, Rui, Patel, Hitisha K., Gutgesell, Lauren M., Zhao, Jiong, Delgado-Rivera, Loruhama, Pham, Thao N.D., Zhao, Huiping, Carlson, Kathryn, Martin, Teresa, Katzenellenbogen, John A., Moore, Terry W., Tonetti, Debra A., Thatcher, Gregory R. J.
Publicado no J Med Chem (2015)

SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites

Por Madhubhani, L.P., Hemachandra, P., Patel, Hitisha, Esala, R., Chandrasena, P., Choi, Jaewoo, Piyankarage, Sujeewa C., Wang, Shuai, Wang, Yijin, Thayer, Emily, Scism, Rob, Michalsen, Bradley T., Xiong, Rui, Siklos, Marton, Bolton, Judy L., Thatcher, Gregory R.J.
Publicado em 2014