A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy

Breast cancer remains a significant cause of death in women and few therapeutic options exist for estrogen receptor negative ER(−) cancers. Epigenetic re-activation of target genes using histone deacetylase (HDAC) inhibitors has been proposed in ER(−) cancers to resensitize to therapy using selectiv...

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Autores principales: Patel, Hitisha K., Siklos, Marton I., Abdelkarim, Hazem, Mendonca, Emma L., Vaidya, Aditya, Petukhov, Pavel A., Thatcher, Gregory R. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962780/
https://ncbi.nlm.nih.gov/pubmed/23956109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300270
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