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A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy
Breast cancer remains a significant cause of death in women and few therapeutic options exist for estrogen receptor negative ER(−) cancers. Epigenetic re-activation of target genes using histone deacetylase (HDAC) inhibitors has been proposed in ER(−) cancers to resensitize to therapy using selectiv...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962780/ https://ncbi.nlm.nih.gov/pubmed/23956109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300270 |
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