Prevention of breast cancer by recapitulation of pregnancy hormone levels

gan Tonetti, Debra A
Cyhoeddwyd 2004

Estradiol-Induced Regression in T47D:A18/PKCα Tumors Requires the Estrogen Receptor And Interaction with the Extracellular Matrix

gan Zhang, Yiyun, Zhao, Huiping, Asztalos, Szilard, Chisamore, Michael, Sitabkhan, Yasmin, Tonetti, Debra A.
Cyhoeddwyd 2009

PKCα and ERβ Are Associated with Triple-Negative Breast Cancers in African American and Caucasian Patients

gan Tonetti, Debra A., Gao, Weihua, Escarzaga, Diana, Walters, Kelly, Szafran, April, Coon, John S.
Cyhoeddwyd 2012

Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer

gan Perez White, Bethany, Molloy, Mary Ellen, Zhao, Huiping, Zhang, Yiyun, Tonetti, Debra A
Cyhoeddwyd 2013

Retraction Note to: Extranuclear ERα is associated with regression of T47D PKCα-overexpressing, tamoxifen-resistant breast cancer

gan White, Bethany Perez, Molloy, Mary Ellen, Zhao, Huiping, Zhang, Yiyun, Tonetti, Debra A.
Cyhoeddwyd yn Mol Cancer (2017)

Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin

gan Pham, Thao N. D., Perez White, Bethany E., Zhao, Huiping, Mortazavi, Fariborz, Tonetti, Debra A.
Cyhoeddwyd yn BMC Cancer (2017)

Novel Selective Estrogen Receptor Downregulators (SERDs) Developed Against Treatment-Resistant Breast Cancer

gan Xiong, Rui, Zhao, Jiong, Gutgesell, Lauren M., Wang, Yueting, Lee, Sue, Karumudi, Bhargava, Zhao, Huiping, Lu, Yunlong, Tonetti, Debra A., Thatcher, Gregory R. J.
Cyhoeddwyd yn J Med Chem (2017)

Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer

gan Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Hanspal, Jay S., Fan, Ping, Xiong, Rui, Tonetti, Debra A., Thatcher, Gregory R.J., Jordan, V. Craig
Cyhoeddwyd yn Mol Pharmacol (2020)

Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbocicl...

gan Li, Yangfeng, Zhao, Jiong, Gutgesell, Lauren M., Shen, Zhengnan, Ratia, Kiira, Dye, Katherine, Dubrovskyi, Oleksii, Zhao, Huiping, Huang, Fei, Tonetti, Debra A., Thatcher, Gregory R. J., Xiong, Rui
Cyhoeddwyd yn J Med Chem (2020)

Click synthesis of estradiol–cyclodextrin conjugates as cell compartment selective estrogens

gan Kim, Hye-Yeong, Sohn, Johann, Wijewickrama, Gihani T., Edirisinghe, Praneeth, Gherezghiher, Teshome, Hemachandra, Madhubani, Lu, Pei-Yi, Chandrasena, R. Esala, Molloy, Mary Ellen, Tonetti, Debra A., Thatcher, Gregory R. J.
Cyhoeddwyd 2009

Novel Selective Estrogen Mimics for the Treatment of Tamoxifen-Resistant Breast Cancer

gan Molloy, Mary Ellen, Perez White, Bethany E., Gherezghiher, Teshome, Michalsen, Bradley T., Xiong, Rui, Patel, Hitisha, Zhao, Huiping, Maximov, Philipp Y., Jordan, V. Craig, Thatcher, Gregory R. J., Tonetti, Debra A.
Cyhoeddwyd yn Mol Cancer Ther (2014)

PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer

gan Zheng, Yu, Wang, Zebin, Bie, Wenjun, Brauer, Patrick M., White, Bethany E. Perez, Li, Jing, Nogueira, Veronique, Raychaudhuri, Pradip, Hay, Nissim, Tonetti, Debra A., Macias, Virgilia, Kajdacsy-Balla, André, Tyner, Angela L.
Cyhoeddwyd 2013

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors

gan Peng, Maoyu, Emmadi, Rajyasree, Wang, Zebin, Wiley, Elizabeth L., Gann, Peter H., Khan, Seema A., Banerji, Nilanjana, McDonald, William, Asztalos, Szilard, Pham, Thao N.D., Tonetti, Debra A., Tyner, Angela L.
Cyhoeddwyd 2014

High incidence of triple negative breast cancers following pregnancy and an associated gene expression signature

gan Asztalos, Szilard, Pham, Thao N., Gann, Peter H., Hayes, Meghan K., Deaton, Ryan, Wiley, Elizabeth L., Emmadi, Rajyasree, Kajdacsy-Balla, Andre, Banerji, Nilanjana, McDonald, William, Khan, Seema A., Tonetti, Debra A.
Cyhoeddwyd yn Springerplus (2015)

Selective human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer

gan Xiong, Rui, Patel, Hitisha K., Gutgesell, Lauren M., Zhao, Jiong, Delgado-Rivera, Loruhama, Pham, Thao N.D., Zhao, Huiping, Carlson, Kathryn, Martin, Teresa, Katzenellenbogen, John A., Moore, Terry W., Tonetti, Debra A., Thatcher, Gregory R. J.
Cyhoeddwyd yn J Med Chem (2015)

Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer

gan Abderrahman, Balkees, Maximov, Philipp Y., Curpan, Ramona F., Fanning, Sean W., Hanspal, Jay S., Fan, Ping, Foulds, Charles E., Chen, Yue, Malovannaya, Anna, Jain, Antrix, Xiong, Rui, Greene, Geoffrey L., Tonetti, Debra A., Thatcher, Gregory R. J., Jordan, V. Craig
Cyhoeddwyd yn Mol Cancer Ther (2020)

Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer

gan Lu, Yunlong, Gutgesell, Lauren M., Xiong, Rui, Zhao, Jiong, Li, Yangfeng, Rosales, Carlo I., Hollas, Michael, Shen, Zhengnan, Gordon-Blake, Jesse, Dye, Katherine, Wang, Yueting, Lee, Sue, Chen, Hu, He, Donghong, Dubrovyskyii, Oleksii, Zhao, Huiping, Huang, Fei, Lasek, Amy W., Tonetti, Debra A., Thatcher, Gregory R. J.
Cyhoeddwyd yn J Med Chem (2019)

G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

gan Andreano, Kaitlyn J., Wardell, Suzanne E., Baker, Jennifer G., Desautels, Taylor K., Baldi, Robert, Chao, Christina A., Heetderks, Kendall A., Bae, Yeeun, Xiong, Rui, Tonetti, Debra A., Gutgesell, Lauren M., Zhao, Jiong, Sorrentino, Jessica A., Thompson, Delita A., Bisi, John E., Strum, Jay C., Thatcher, Gregory R. J., Norris, John D.
Cyhoeddwyd yn Breast Cancer Res Treat (2020)

Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches

gan Rizzo, Paola, Miao, Haixi, D'Souza, Gwendolyn, Osipo, Clodia, Yun, Jieun, Zhao, Huiping, Mascarenhas, Joaquina, Wyatt, Debra, Antico, Giovanni, Hao, Lu, Yao, Katharine, Rajan, Prabha, Hicks, Chindo, Siziopikou, Kalliopi, Selvaggi, Suzanne, Bashir, Amina, Bhandari, Deepali, Marchese, Adriano, Lendahl, Urban, Qin, Jian-Zhong, Tonetti, Debra A., Albain, Kathy, Nickoloff, Brian J., Miele, Lucio
Cyhoeddwyd yn Cancer Res (2008)