The Protease-activated Receptor-2-specific Agonists 2-Aminothiazol-4-yl-LIGRL-NH(2) and 6-Aminonicotinyl-LIGRL-NH(2) Stimulate Multiple Signaling Pathways to Induce Physiological R...

door Flynn, Andrea N., Tillu, Dipti V., Asiedu, Marina N., Hoffman, Justin, Vagner, Josef, Price, Theodore J., Boitano, Scott
Gepubliceerd in 2011

Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain

door Tillu, Dipti V, Melemedjian, Ohannes K, Asiedu, Marina N, Qu, Ning, De Felice, Milena, Dussor, Gregory, Price, Theodore J
Gepubliceerd in 2012

Lanthanide labeling of a potent protease activated receptor-2 agonist for time-resolved fluorescence analysis

door Hoffman, Justin, Flynn, Andrea N., Tillu, Dipti V., Zhang, Zhenyu, Patek, Renata, Price, Theodore J., Vagner, Josef, Boitano, Scott
Gepubliceerd in 2012

IL-6- and NGF-Induced Rapid Control of Protein Synthesis and Nociceptive Plasticity via Convergent Signaling to the eIF4F Complex

door Melemedjian, Ohannes K., Asiedu, Marina N., Tillu, Dipti V., Peebles, Katherine A., Yan, Jin, Ertz, Natalie, Dussor, Gregory O., Price, Theodore J.
Gepubliceerd in 2010

Spinal Protein Kinase M ζ Underlies the Maintenance Mechanism of Persistent Nociceptive Sensitization

door Asiedu, Marina N., Tillu, Dipti V., Melemedjian, Ohannes K., Shy, Adia, Sanoja, Raul, Bodell, Bryce, Ghosh, Sourav, Porreca, Frank, Price, Theodore J.
Gepubliceerd in 2011

Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity

door Melemedjian, Ohannes K, Tillu, Dipti V, Moy, Jamie K, Asiedu, Marina N, Mandell, Edward K, Ghosh, Sourav, Dussor, Gregory, Price, Theodore J
Gepubliceerd in 2014

Development and Evaluation of Small Peptidomimetic Ligands to Protease-Activated Receptor-2 (PAR(2)) through the Use of Lipid Tethering

door Boitano, Scott, Hoffman, Justin, Tillu, Dipti V., Asiedu, Marina N., Zhang, Zhenyu, Sherwood, Cara L., Wang, Yan, Dong, Xinzhong, Price, Theodore J., Vagner, Josef
Gepubliceerd in 2014

Protease activated receptor 2 (PAR(2)) activation is sufficient to induce the transition to a chronic pain state

door Tillu, Dipti V, Hassler, Shayne N, Burgos-Vega, Carolina C, Quinn, Tammie L, Sorge, Robert E, Dussor, Gregory, Boitano, Scott, Vagner, Josef, J Price, Theodore
Gepubliceerd in Pain (2015)

Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice

door Burton, Michael D, Tillu, Dipti V, Mazhar, Khadijah, Mejia, Galo L, Asiedu, Marina N, Inyang, Kufreobong, Hughes, Travis, Lian, Bo, Dussor, Gregory, Price, Theodore J
Gepubliceerd in Neuroscience (2017)

BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state

door Melemedjian, Ohannes K, Tillu, Dipti V, Asiedu, Marina N, Mandell, Edward K, Moy, Jamie K, Blute, Victoria M, Taylor, Caleb J, Ghosh, Sourav, Price, Theodore J
Gepubliceerd in 2013

Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering

door Flynn, Andrea N., Hoffman, Justin, Tillu, Dipti V., Sherwood, Cara L., Zhang, Zhenyu, Patek, Renata, Asiedu, Marina N. K., Vagner, Josef, Price, Theodore J., Boitano, Scott
Gepubliceerd in 2013

Temporal and sex differences in the role of BDNF/TrkB signaling in hyperalgesic priming in mice and rats

door Moy, Jamie K., Szabo-Pardi, Thomas, Tillu, Dipti V., Megat, Salim, Pradhan, Grishma, Kume, Moeno, Asiedu, Marina N., Burton, Michael D., Dussor, Gregory, Price, Theodore J.
Gepubliceerd in Neurobiol Pain (2018)

The novel PAR2 ligand C391 blocks multiple PAR2 signalling pathways in vitro and in vivo

door Boitano, Scott, Hoffman, Justin, Flynn, Andrea N, Asiedu, Marina N, Tillu, Dipti V, Zhang, Zhenyu, Sherwood, Cara L, Rivas, Candy M, DeFea, Kathryn A, Vagner, Josef, Price, Theodore J
Gepubliceerd in Br J Pharmacol (2015)

Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

door Melemedjian, Ohannes K, Asiedu, Marina N, Tillu, Dipti V, Sanoja, Raul, Yan, Jin, Lark, Arianna, Khoutorsky, Arkady, Johnson, Jessica, Peebles, Katherine A, Lepow, Talya, Sonenberg, Nahum, Dussor, Gregory, Price, Theodore J
Gepubliceerd in 2011

Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain

door Hanamura, Kenji, Washburn, Halley R., Sheffler-Collins, Sean I., Xia, Nan L., Henderson, Nathan, Tillu, Dipti V., Hassler, Shayne, Spellman, Daniel S., Zhang, Guoan, Neubert, Thomas A., Price, Theodore J., Dalva, Matthew B.
Gepubliceerd in PLoS Biol (2017)

Spinal Dopaminergic Projections Control the Transition to Pathological Pain Plasticity via a D(1)/D(5)-Mediated Mechanism

door Kim, Ji-Young V., Tillu, Dipti V., Quinn, Tammie L., Mejia, Galo L., Shy, Adia, Asiedu, Marina N.K., Murad, Elaine, Schumann, Alan P., Totsch, Stacie K., Sorge, Robert E., Mantyh, Patrick W., Dussor, Gregory, Price, Theodore J.
Gepubliceerd in J Neurosci (2015)