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Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice

New therapeutics to manage post-surgical pain are needed to mitigate the liabilities of opioid and other analgesics. Our previous work shows that key modulators of excitability in peripheral nociceptors, such as extracellular signal-regulated kinases (ERK) are inhibited by activation of adenosine mo...

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Bibliografische gegevens
Gepubliceerd in:Neuroscience
Hoofdauteurs: Burton, Michael D, Tillu, Dipti V, Mazhar, Khadijah, Mejia, Galo L, Asiedu, Marina N, Inyang, Kufreobong, Hughes, Travis, Lian, Bo, Dussor, Gregory, Price, Theodore J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641389/
https://ncbi.nlm.nih.gov/pubmed/28729062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.07.020
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