Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice

AMP-activated protein kinase (AMPK) is an energy-sensing kinase that has emerged as a novel therapeutic target for pain due to its ability to inhibit mechanistic target of rapamycin (mTOR) and mitogen activated protein kinase (MAPK) signaling, two signaling pathways that are linked to pain promotion...

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Detalhes bibliográficos
Publicado no:Neurobiol Pain
Main Authors: Inyang, Kufreobong E., McDougal, Timothy A., Ramirez, Eric D., Williams, Marisa, Laumet, Geoffroy, Kavelaars, Annemieke, Heijnen, Cobi J., Burton, Michael, Dussor, Gregory, Price, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804652/
https://ncbi.nlm.nih.gov/pubmed/31650090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2019.100037
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