Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice

AMP-activated protein kinase (AMPK) is an energy-sensing kinase that has emerged as a novel therapeutic target for pain due to its ability to inhibit mechanistic target of rapamycin (mTOR) and mitogen activated protein kinase (MAPK) signaling, two signaling pathways that are linked to pain promotion...

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Detalles Bibliográficos
Publicado en:Neurobiol Pain
Main Authors: Inyang, Kufreobong E., McDougal, Timothy A., Ramirez, Eric D., Williams, Marisa, Laumet, Geoffroy, Kavelaars, Annemieke, Heijnen, Cobi J., Burton, Michael, Dussor, Gregory, Price, Theodore J.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Original Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804652/
https://ncbi.nlm.nih.gov/pubmed/31650090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2019.100037
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