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Spinal inhibition of P2XR or p38 signaling disrupts hyperalgesic priming in male, but not female, mice

Recent studies have demonstrated sexual dimorphisms in the mechanisms contributing to the development of chronic pain. Here we tested the hypothesis that microglia might preferentially regulate hyperalgesic priming in male mice. We based this hypothesis on evidence that microglia preferentially cont...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Paige, Candler, Maruthy, Gayathri Batchalli, Mejia, Galo, Dussor, Gregory, Price, Theodore
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127868/
https://ncbi.nlm.nih.gov/pubmed/29913243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.06.012
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