AMPK activation regulates P-body dynamics in mouse sensory neurons in vitro and in vivo

Increased mRNA translation in sensory neurons following peripheral nerve injury contributes to the induction and maintenance of chronic neuropathic pain. Metformin, a common anti-diabetic drug and an activator of AMP-activated protein kinase (AMPK), inhibits cap-dependent mRNA translation and revers...

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Vydáno v:Neurobiol Pain
Hlavní autoři: Paige, Candler, Mejia, Galo, Dussor, Gregory, Price, Theodore
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506165/
https://ncbi.nlm.nih.gov/pubmed/31080914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2018.100026
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