Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity

Transcriptional regulation of genes by cyclic AMP response element binding protein (CREB) is essential for the maintenance of long-term memory. Moreover, retrograde axonal trafficking of CREB in response to nerve growth factor (NGF) is critical for the survival of developing primary sensory neurons....

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Detalhes bibliográficos
Main Authors: Melemedjian, Ohannes K, Tillu, Dipti V, Moy, Jamie K, Asiedu, Marina N, Mandell, Edward K, Ghosh, Sourav, Dussor, Gregory, Price, Theodore J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091745/
https://ncbi.nlm.nih.gov/pubmed/24993495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-45
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