BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state

BACKGROUND: Chronic pain is an important medical problem affecting hundreds of millions of people worldwide. Mechanisms underlying the maintenance of chronic pain states are poorly understood but the elucidation of such mechanisms have the potential to reveal novel therapeutics capable of reversing...

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Autori principali: Melemedjian, Ohannes K, Tillu, Dipti V, Asiedu, Marina N, Mandell, Edward K, Moy, Jamie K, Blute, Victoria M, Taylor, Caleb J, Ghosh, Sourav, Price, Theodore J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608966/
https://ncbi.nlm.nih.gov/pubmed/23510079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-12
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