IL-6- and NGF-Induced Rapid Control of Protein Synthesis and Nociceptive Plasticity via Convergent Signaling to the eIF4F Complex

Despite the emergence of translational control pathways as mediators of nociceptive sensitization, effector molecules and mechanisms responsible for modulating activity in these pathways in pain conditions are largely unknown. We demonstrate that two major algogens, the cytokine interleukin 6 (IL-6)...

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Auteurs principaux: Melemedjian, Ohannes K., Asiedu, Marina N., Tillu, Dipti V., Peebles, Katherine A., Yan, Jin, Ertz, Natalie, Dussor, Gregory O., Price, Theodore J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056511/
https://ncbi.nlm.nih.gov/pubmed/21068317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3947-10.2010
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