Protease activated receptor 2 (PAR(2)) activation is sufficient to induce the transition to a chronic pain state

Protease Activated Receptor Type 2 (PAR(2)) is known to play an important role in inflammatory, visceral and cancer-evoked pain based on studies using PAR(2) knockout (PAR(2)(−/−)) mice. Here we have tested the hypothesis that specific activation of PAR(2) is sufficient to induce a chronic pain stat...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Tillu, Dipti V, Hassler, Shayne N, Burgos-Vega, Carolina C, Quinn, Tammie L, Sorge, Robert E, Dussor, Gregory, Boitano, Scott, Vagner, Josef, J Price, Theodore
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589228/
https://ncbi.nlm.nih.gov/pubmed/25734998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000125
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