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Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

Neuropathic pain is a debilitating clinical condition with few efficacious treatments, warranting development of novel therapeutics. We hypothesized that dysregulated translation regulation pathways may underlie neuropathic pain. Peripheral nerve injury induced reorganization of translation machiner...

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Detalhes bibliográficos
Main Authors: Melemedjian, Ohannes K, Asiedu, Marina N, Tillu, Dipti V, Sanoja, Raul, Yan, Jin, Lark, Arianna, Khoutorsky, Arkady, Johnson, Jessica, Peebles, Katherine A, Lepow, Talya, Sonenberg, Nahum, Dussor, Gregory, Price, Theodore J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186752/
https://ncbi.nlm.nih.gov/pubmed/21936900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-70
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