Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

Neuropathic pain is a debilitating clinical condition with few efficacious treatments, warranting development of novel therapeutics. We hypothesized that dysregulated translation regulation pathways may underlie neuropathic pain. Peripheral nerve injury induced reorganization of translation machiner...

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Autori principali: Melemedjian, Ohannes K, Asiedu, Marina N, Tillu, Dipti V, Sanoja, Raul, Yan, Jin, Lark, Arianna, Khoutorsky, Arkady, Johnson, Jessica, Peebles, Katherine A, Lepow, Talya, Sonenberg, Nahum, Dussor, Gregory, Price, Theodore J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186752/
https://ncbi.nlm.nih.gov/pubmed/21936900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-70
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