The future of the β-lactams

door Llarrull, Leticia I, Testero, Sebastian A, Fisher, Jed F, Mobashery, Shahriar
Gepubliceerd in Curr Opin Microbiol (2010)

Mechanistic Basis for the Emergence of Catalytic Competence against Carbapenem Antibiotics by the GES Family of β-Lactamases

door Frase, Hilary, Shi, Qicun, Testero, Sebastian A., Mobashery, Shahriar, Vakulenko, Sergei B.
Gepubliceerd in 2009

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases

door Testero, Sebastian A., Bouley, Renee, Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Gepubliceerd in 2010

Exploring the functional space of thiiranes as gelatinase inhibitors using click chemistry

door Testero, Sebastian A., Llarrull, Leticia I., Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Gepubliceerd in ARKIVOC (2011)

Sulfonate-Containing Thiiranes as Selective Gelatinase Inhibitors

door Testero, Sebastian A., Lee, Mijoon, Staran, Rachel T., Espahbodi, Mana, Llarrull, Leticia I., Toth, Marta, Mobashery, Shahriar, Chang, Mayland
Gepubliceerd in 2010

Regiospecific Syntheses of 6α-(1R-hydroxyoctyl)penicillanic acid and 6β-(1R-hydroxyoctyl)penicillanic acid as Mechanistic Probes of Class D β-Lactamases

door Testero, Sebastian A., O’Daniel, Peter I., Shi, Qicun, Lee, Mijoon, Hesek, Dusan, Ishiwata, Akihiro, Noll, Bruce C., Mobashery, Shahriar
Gepubliceerd in 2009

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library

door Testero, Sebastián A., Granados, Carla, Fernández, Daniel, Gallego, Pablo, Covaleda, Giovanni, Reverter, David, Vendrell, Josep, Avilés, Francesc X., Pallarès, Irantzu, Mobashery, Shahriar
Gepubliceerd in ACS Med Chem Lett (2017)

Hydrolytic Mechanism of OXA-58 Enzyme, a Carbapenem-hydrolyzing Class D β-Lactamase from Acinetobacter baumannii

door Verma, Vidhu, Testero, Sebastian A., Amini, Kaveh, Wei, William, Liu, Jerome, Balachandran, Naresh, Monoharan, Tharseekan, Stynes, Siobhan, Kotra, Lakshmi P., Golemi-Kotra, Dasantila
Gepubliceerd in 2011

Exploration of the Structure-Activity Relationship of 1,2,4-Oxadiazole Antibiotics

door Ding, Derong, Boudreau, Marc A., Leemans, Erika, Spink, Edward, Yamaguchi, Takao, Testero, Sebastian A., O’Daniel, Peter I., Lastochkin, Elena, Chang, Mayland, Mobashery, Shahriar
Gepubliceerd in Bioorg Med Chem Lett (2015)

Three-Dimensional QSAR Analysis and Design of New 1,2,4-Oxadiazole Antibacterials

door Leemans, Erika, Mahasenan, Kiran V., Kumarasiri, Malika, Spink, Edward, Ding, Derong, O’Daniel, Peter, Boudreau, Marc A., Lastochkin, Elena, Testero, Sebastian A., Yamaguchi, Takao, Lee, Mijoon, Hesek, Dusan, Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Gepubliceerd in Bioorg Med Chem Lett (2015)

Structure–Activity Relationship for the Oxadiazole Class of Antibiotics

door Spink, Edward, Ding, Derong, Peng, Zhihong, Boudreau, Marc A., Leemans, Erika, Lastochkin, Elena, Song, Wei, Lichtenwalter, Katerina, O’Daniel, Peter I., Testero, Sebastian A., Pi, Hualiang, Schroeder, Valerie A., Wolter, William R., Antunes, Nuno T., Suckow, Mark A., Vakulenko, Sergei, Chang, Mayland, Mobashery, Shahriar
Gepubliceerd in J Med Chem (2015)

Structure–Activity Relationship for the Oxadiazole Class of Antibacterials

door Boudreau, Marc A., Ding, Derong, Meisel, Jayda E., Janardhanan, Jeshina, Spink, Edward, Peng, Zhihong, Qian, Yuanyuan, Yamaguchi, Takao, Testero, Sebastian A., O’Daniel, Peter I., Leemans, Erika, Lastochkin, Elena, Song, Wei, Schroeder, Valerie A., Wolter, William R., Suckow, Mark A., Mobashery, Shahriar, Chang, Mayland
Gepubliceerd in ACS Med Chem Lett (2019)

Discovery of a New Class of Non-β-lactam Inhibitors of Penicillin-Binding Proteins with Gram-Positive Antibacterial Activity

door O’Daniel, Peter I., Peng, Zhihong, Pi, Hualiang, Testero, Sebastian A., Ding, Derong, Spink, Edward, Leemans, Erika, Boudreau, Marc A., Yamaguchi, Takao, Schroeder, Valerie A., Wolter, William R., Llarrull, Leticia I., Song, Wei, Lastochkin, Elena, Kumarasiri, Malika, Antunes, Nuno T., Espahbodi, Mana, Lichtenwalter, Katerina, Suckow, Mark A., Vakulenko, Sergei, Mobashery, Shahriar, Chang, Mayland
Gepubliceerd in 2014