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Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases

The copper-mediated and non-basic oxidative cross-coupling of organotrifluoroborates with phenols was applied to elaboration of the structures of thiirane-based inhibitors of matrix metalloproteinases. By revision of the synthetic sequence to allow this cross-coupling as the final step, and taking a...

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Autori principali: Testero, Sebastian A., Bouley, Renee, Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081985/
https://ncbi.nlm.nih.gov/pubmed/21256011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.12.076
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