Identifying Cancer-Relevant Mutations in the DLC START Domain Using Evolutionary and Structure-Function Analyses

di Holub, Ashton S., Bouley, Renee A., Petreaca, Ruben C., Husbands, Aman Y.
Pubblicato in Int J Mol Sci (2020)

Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinases

di Testero, Sebastian A., Bouley, Renee, Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Pubblicazione 2010

Structural basis of lysosomal phospholipase A(2) inhibition by Zn(2+)

di Bouley, Renee A., Hinkovska-Galcheva, Vania, Shayman, James A., Tesmer, John J. G.
Pubblicato in Biochemistry (2019)

Utilizing a Structure-Based Docking Approach to Develop Potent G Protein-Coupled Receptor Kinase (GRK) 2 and 5 Inhibitors

di Waldschmidt, Helen V., Bouley, Renee, Kirchhoff, Paul D., Lee, Pil, Tesmer, John J. G., Larsen, Scott D.
Pubblicato in Bioorg Med Chem Lett (2018)

Synthesis and Evaluation of 1,2,4-Triazolo[1,5-a]pyrimidines as Antibacterial Agents Against Enterococcus faecium

di Wang, Huan, Lee, Mijoon, Peng, Zhihong, Blázquez, Blas, Lastochkin, Elena, Kumarasiri, Malika, Bouley, Renee, Chang, Mayland, Mobashery, Shahriar
Pubblicato in J Med Chem (2015)

Generation of Highly Selective, Potent, and Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors

di Rowlands, Rachel A., Chen, Qiuyan, Bouley, Renee A., Avramova, Larisa V., Tesmer, John J. G., White, Andrew D.
Pubblicato in J Med Chem (2021)

Conformational dynamics in penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus, allosteric communication network and enablement of catalysis

di Mahasenan, Kiran V., Molina, Rafael, Bouley, Renee, Batuecas, María T., Fisher, Jed F., Hermoso, Juan A., Chang, Mayland, Mobashery, Shahriar
Pubblicato in J Am Chem Soc (2017)

Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A(2)

di Hinkovska-Galcheva, Vania, Kelly, Robert, Manthei, Kelly A., Bouley, Renee, Yuan, Wenmin, Schwendeman, Anna, Tesmer, John J. G., Shayman, James A.
Pubblicato in J Lipid Res (2018)

A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor

di Bouley, Renee A., Weinberg, Zara Y., Waldschmidt, Helen V., Yen, Yu-Chen, Larsen, Scott D., Puthenveedu, Manojkumar A., Tesmer, John J.G.
Pubblicato in Mol Pharmacol (2020)

Structure–Activity Relationship for the 4(3H)-Quinazolinone Antibacterials

di Bouley, Renee, Ding, Derong, Peng, Zhihong, Bastian, Maria, Lastochkin, Elena, Song, Wei, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Pubblicato in J Med Chem (2016)

Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors

di Rowlands, Rachel A., Cato, M. Claire, Waldschmidt, Helen V., Bouley, Renee A., Chen, Qiuyan, Avramova, Larisa, Larsen, Scott D., Tesmer, John J. G., White, Andrew D.
Pubblicato in ACS Med Chem Lett (2019)

Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein–Coupled Receptor Kinase 2 Inhibitors

di Bouley, Renee, Waldschmidt, Helen V., Cato, M. Claire, Cannavo, Alessandro, Song, Jianliang, Cheung, Joseph Y., Yao, Xin-Qiu, Koch, Walter J., Larsen, Scott D., Tesmer, John J. G.
Pubblicato in Mol Pharmacol (2017)

Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA

di Gonzales, Patrick R., Pesesky, Mitchell W., Bouley, Renee, Ballard, Anna, Biddy, Brent A., Suckow, Mark A., Wolter, William R., Schroeder, Valerie A., Burnham, Carey-Ann D., Mobashery, Shahriar, Chang, Mayland, Dantas, Gautam
Pubblicato in Nat Chem Biol (2015)

The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus

di Janardhanan, Jeshina, Bouley, Renee, Martínez-Caballero, Siseth, Peng, Zhihong, Batuecas-Mordillo, Mayte, Meisel, Jayda E., Ding, Derong, Schroeder, Valerie A., Wolter, William R., Mahasenan, Kiran V., Hermoso, Juan A., Mobashery, Shahriar, Chang, Mayland
Pubblicato in Antimicrob Agents Chemother (2019)

Discovery of Antibiotic (E)-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one

di Bouley, Renee, Kumarasiri, Malika, Peng, Zhihong, Otero, Lisandro H., Song, Wei, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Lastochkin, Elena, Antunes, Nuno T., Pi, Hualiang, Vakulenko, Sergei, Hermoso, Juan A., Chang, Mayland, Mobashery, Shahriar
Pubblicato in J Am Chem Soc (2015)