Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A(2)

Lysosomal phospholipase A2 (LPLA(2)) is characterized by broad substrate recognition, peak activity at acidic pH, and the transacylation of lipophilic alcohols, especially N-acetyl-sphingosine. Prior structural analysis of LPLA(2) revealed the presence of an atypical acidic residue, Asp13, in the ot...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Lipid Res
Asıl Yazarlar: Hinkovska-Galcheva, Vania, Kelly, Robert, Manthei, Kelly A., Bouley, Renee, Yuan, Wenmin, Schwendeman, Anna, Tesmer, John J. G., Shayman, James A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027918/
https://ncbi.nlm.nih.gov/pubmed/29724779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M084012
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller