The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus

The quinazolinones are a new class of antibacterials with in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA). The quinazolinones target cell wall biosynthesis and have a unique mechanism of action by binding to the allosteric site of penicillin-binding protein 2a (PBP 2a). W...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Janardhanan, Jeshina, Bouley, Renee, Martínez-Caballero, Siseth, Peng, Zhihong, Batuecas-Mordillo, Mayte, Meisel, Jayda E., Ding, Derong, Schroeder, Valerie A., Wolter, William R., Mahasenan, Kiran V., Hermoso, Juan A., Mobashery, Shahriar, Chang, Mayland
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496080/
https://ncbi.nlm.nih.gov/pubmed/30858202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02637-18
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars