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Exploring the functional space of thiiranes as gelatinase inhibitors using click chemistry
A series of 4-[(triazolyl)methoxy]phenyl analogs of the phenoxyphenyl-substituted thiirane SB-3CT 1 was evaluated for its ability to inhibit gelatinases, members of the matrix metalloproteinase family of enzymes. The triazole segment of these inhibitors was assembled using the Meldal-Sharpless coppe...
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| 發表在: | ARKIVOC |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7412954/ https://ncbi.nlm.nih.gov/pubmed/32774191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3998/ark.5550190.0012.719 |
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