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Conformational Analyses of Thiirane-Based Gelatinase Inhibitors

SB-3CT is a thiirane-containing inhibitor of the gelatinase class of matrix metalloprotease enzymes. In support of the mechanistic study of this inhibition, the conformational analyses of SB-3CT (and of two methyl-substituted derivatives) were undertaken using x-ray crystallography and molecular dyn...

詳細記述

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書誌詳細
主要な著者: Lee, Mijoon, Hesek, Dusan, Shi, Qicun, Noll, Bruce C., Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
フォーマット: Artigo
言語:Inglês
出版事項: 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286628/
https://ncbi.nlm.nih.gov/pubmed/18083555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.11.131
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