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The future of the β-lactams

In the 80 years since their discovery the β-lactam antibiotics have progressed through structural generations, each in response to the progressive evolution of bacterial resistance mechanisms. The generational progression was driven by the ingenious, but largely empirical, manipulation of structure...

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Bibliografische gegevens
Gepubliceerd in:Curr Opin Microbiol
Hoofdauteurs: Llarrull, Leticia I, Testero, Sebastian A, Fisher, Jed F, Mobashery, Shahriar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6878888/
https://ncbi.nlm.nih.gov/pubmed/20888287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2010.09.008
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