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The future of the β-lactams
In the 80 years since their discovery the β-lactam antibiotics have progressed through structural generations, each in response to the progressive evolution of bacterial resistance mechanisms. The generational progression was driven by the ingenious, but largely empirical, manipulation of structure...
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| Publicado en: | Curr Opin Microbiol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6878888/ https://ncbi.nlm.nih.gov/pubmed/20888287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2010.09.008 |
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