Three-Dimensional QSAR Analysis and Design of New 1,2,4-Oxadiazole Antibacterials

The oxadiazole antibacterials, a class of newly discovered compounds that are active against Gram-positive bacteria, target bacterial cell-wall biosynthesis by inhibition of a family of essential enzymes, the penicillin-binding proteins. Ligand-based 3D-QSAR analyses by comparative molecular field a...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Leemans, Erika, Mahasenan, Kiran V., Kumarasiri, Malika, Spink, Edward, Ding, Derong, O’Daniel, Peter, Boudreau, Marc A., Lastochkin, Elena, Testero, Sebastian A., Yamaguchi, Takao, Lee, Mijoon, Hesek, Dusan, Fisher, Jed F., Chang, Mayland, Mobashery, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849414/
https://ncbi.nlm.nih.gov/pubmed/26733473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.12.041
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