Integrating platelet and coagulation activation in fibrin clot formation

מאת Swieringa, Frauke, Spronk, Henri M.H., Heemskerk, Johan W.M., van der Meijden, Paola E.J.
הוצא לאור ב Res Pract Thromb Haemost (2018)

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis

מאת Provenzale, Isabella, Brouns, Sanne L. N., van der Meijden, Paola E. J., Swieringa, Frauke, Heemskerk, Johan W. M.
הוצא לאור ב Micromachines (Basel) (2019)

Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow

מאת Swieringa, Frauke, Kuijpers, Marijke J. E., Lamers, Moniek M. E., van der Meijden, Paola E. J., Heemskerk, Johan W. M.
הוצא לאור ב Haematologica (2015)

Key role of integrin α(IIb)β(3) signaling to Syk kinase in tissue factor-induced thrombin generation

מאת van der Meijden, Paola E. J., Feijge, Marion A. H., Swieringa, Frauke, Gilio, Karen, Nergiz-Unal, Reyhan, Hamulyák, Karly, Heemskerk, Johan W. M.
יצא לאור 2012

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

מאת Whyte, Claire S., Swieringa, Frauke, Mastenbroek, Tom G., Lionikiene, Ausra S., Lancé, Marcus D., van der Meijden, Paola E. J., Heemskerk, Johan W. M., Mutch, Nicola J.
הוצא לאור ב Blood (2015)

Combined Quantification of the Global Proteome, Phosphoproteome, and Proteolytic Cleavage to Characterize Altered Platelet Functions in the Human Scott Syndrome

מאת Solari, Fiorella A., Mattheij, Nadine J.A., Burkhart, Julia M., Swieringa, Frauke, Collins, Peter W., Cosemans, Judith M.E.M., Sickmann, Albert, Heemskerk, Johan W.M., Zahedi, René P.
הוצא לאור ב Mol Cell Proteomics (2016)

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions

מאת Huang, Jingnan, Swieringa, Frauke, Solari, Fiorella A., Provenzale, Isabella, Grassi, Luigi, De Simone, Ilaria, Baaten, Constance C. F. M. J., Cavill, Rachel, Sickmann, Albert, Frontini, Mattia, Heemskerk, Johan W. M.
הוצא לאור ב Sci Rep (2021)

Suppressive Role of Tissue Factor Pathway Inhibitor-α in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength

מאת Thomassen, Stella, Mastenbroek, Tom G., Swieringa, Frauke, Winckers, Kristien, Feijge, Marion A.H., Schrijver, Roy, Cosemans, Judith M.E.M., Maroney, Susan A., Mast, Alan E., Hackeng, Tilman M., Heemskerk, Johan W.M.
הוצא לאור ב Thromb Haemost (2018)

Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects

מאת Baaten, Constance C. F. M. J., Swieringa, Frauke, Misztal, Tomasz, Mastenbroek, Tom G., Feijge, Marion A. H., Bock, Paul E., Donners, Marjo M. P. C., Collins, Peter W., Li, Renhao, van der Meijden, Paola E. J., Heemskerk, Johan W. M.
הוצא לאור ב Blood Adv (2018)

Gradual increase in thrombogenicity of juvenile platelets formed upon offset of prasugrel medication

מאת Baaten, Constance C. F. M. J., Veenstra, Leo F., Wetzels, Rick, van Geffen, Johanna P., Swieringa, Frauke, de Witt, Susanne M., Henskens, Yvonne M. C., Crijns, Harry, Nylander, Sven, van Giezen, J. J. J., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
הוצא לאור ב Haematologica (2015)

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

מאת Lepropre, Sophie, Kautbally, Shakeel, Octave, Marie, Ginion, Audrey, Onselaer, Marie-Blanche, Steinberg, Gregory R., Kemp, Bruce E., Hego, Alexandre, Wéra, Odile, Brouns, Sanne, Swieringa, Frauke, Giera, Martin, Darley-Usmar, Victor M., Ambroise, Jérôme, Guigas, Bruno, Heemskerk, Johan, Bertrand, Luc, Oury, Cécile, Beauloye, Christophe, Horman, Sandrine
הוצא לאור ב Blood (2018)

Identification of platelet function defects by multi-parameter assessment of thrombus formation

מאת de Witt, Susanne M., Swieringa, Frauke, Cavill, Rachel, Lamers, Moniek M. E., van Kruchten, Roger, Mastenbroek, Tom, Baaten, Constance, Coort, Susan, Pugh, Nicholas, Schulz, Ansgar, Scharrer, Inge, Jurk, Kerstin, Zieger, Barbara, Clemetson, Kenneth J., Farndale, Richard W., Heemskerk, Johan W. M., Cosemans, Judith M.E.M.
יצא לאור 2014

Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy

מאת Baaten, Constance C. F. M. J., Moenen, Floor C. J. I., Henskens, Yvonne M. C., Swieringa, Frauke, Wetzels, Rick J. H., van Oerle, René, Heijnen, Harry F. G., ten Cate, Hugo, Holloway, Graham P., Beckers, Erik A. M., Heemskerk, Johan W. M., van der Meijden, Paola E. J.
הוצא לאור ב Haematologica (2018)

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome

מאת van Geffen, Johanna P., Swieringa, Frauke, van Kuijk, Kim, Tullemans, Bibian M. E., Solari, Fiorella A., Peng, Bing, Clemetson, Kenneth J., Farndale, Richard W., Dubois, Ludwig J., Sickmann, Albert, Zahedi, René P., Ahrends, Robert, Biessen, Erik A. L., Sluimer, Judith C., Heemskerk, Johan W. M., Kuijpers, Marijke J. E.
הוצא לאור ב Sci Rep (2020)

Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation

מאת Brouns, Sanne L. N., van Geffen, Johanna P., Campello, Elena, Swieringa, Frauke, Spiezia, Luca, van Oerle, René, Provenzale, Isabella, Verdoold, Remco, Farndale, Richard W., Clemetson, Kenneth J., Spronk, Henri M. H., van der Meijden, Paola E. J., Cavill, Rachel, Kuijpers, Marijke J. E., Castoldi, Elisabetta, Simioni, Paolo, Heemskerk, Johan W. M.
הוצא לאור ב Sci Rep (2020)

High-throughput elucidation of thrombus formation reveals sources of platelet function variability

מאת van Geffen, Johanna P., Brouns, Sanne L.N., Batista, Joana, McKinney, Harriet, Kempster, Carly, Nagy, Magdolna, Sivapalaratnam, Suthesh, Baaten, Constance C.F.M.J., Bourry, Nikki, Frontini, Mattia, Jurk, Kerstin, Krause, Manuela, Pillitteri, Daniele, Swieringa, Frauke, Verdoold, Remco, Cavill, Rachel, Kuijpers, Marijke J. E., Ouwehand, Willem H., Downes, Kate, Heemskerk, Johan W.M.
הוצא לאור ב Haematologica (2019)

Coated platelets function in platelet-dependent fibrin formation via integrin α(IIb)β(3) and transglutaminase factor XIII

מאת Mattheij, Nadine J.A., Swieringa, Frauke, Mastenbroek, Tom G., Berny-Lang, Michelle A., May, Frauke, Baaten, Constance C.F.M.J., van der Meijden, Paola E.J., Henskens, Yvonne M.C., Beckers, Erik A.M., Suylen, Dennis P.L., Nolte, Marc W., Hackeng, Tilman M., McCarty, Owen J.T., Heemskerk, Johan W.M., Cosemans, Judith M.E.M.
הוצא לאור ב Haematologica (2016)

Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS

מאת Swieringa, Frauke, Solari, Fiorella A., Pagel, Oliver, Beck, Florian, Huang, Jingnan, Feijge, Marion A. H., Jurk, Kerstin, Körver-Keularts, Irene M. L. W., Mattheij, Nadine J. A., Faber, Jörg, Pohlenz, Joachim, Russo, Alexandra, Stumpel, Connie T. R. M., Schrander, Dirk E., Zieger, Barbara, van der Meijden, Paola E. J., Zahedi, René P., Sickmann, Albert, Heemskerk, Johan W. M.
הוצא לאור ב Sci Rep (2020)

A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding

מאת Baaten, Constance C. F. M. J., Meacham, Stuart, de Witt, Susanne M., Feijge, Marion A. H., Adams, David J., Akkerman, Jan-Willem N., Cosemans, Judith M. E. M., Grassi, Luigi, Jupe, Steve, Kostadima, Myrto, Mattheij, Nadine J. A., Prins, Martin H., Ramirez-Solis, Ramiro, Soehnlein, Oliver, Swieringa, Frauke, Weber, Christian, White, Jacqueline K., Ouwehand, Willem H., Heemskerk, Johan W. M.
הוצא לאור ב Blood (2018)