Macropinocytic entry of isolated mitochondria in epidermal growth factor-activated human osteosarcoma cells

द्वारा Patel, Dipali, Rorbach, Joanna, Downes, Kate, Szukszto, Maciej J., Pekalski, Marcin L., Minczuk, Michal
में प्रकाशित Sci Rep (2017)

Evidence of association with type 1 diabetes in the SLC11A1 gene region

द्वारा Yang, Jennie HM, Downes, Kate, Howson, Joanna MM, Nutland, Sarah, Stevens, Helen E, Walker, Neil M, Todd, John A
प्रकाशित 2011

Clinical management, ethics and informed consent related to multi‐gene panel‐based high throughput sequencing testing for platelet disorders: Communication from the SSC of the ISTH...

द्वारा Downes, Kate, Borry, Pascal, Ericson, Katrin, Gomez, Keith, Greinacher, Andreas, Lambert, Michele, Leinoe, Eva, Noris, Patrizia, Van Geet, Chris, Freson, Kathleen
में प्रकाशित J Thromb Haemost (2020)

Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes

द्वारा Downes, Kate, Pekalski, Marcin, Angus, Karen L., Hardy, Matthew, Nutland, Sarah, Smyth, Deborah J., Walker, Neil M., Wallace, Chris, Todd, John A.
प्रकाशित 2010

TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway

द्वारा Wang, Jun, Ferreira, Ricardo, Lu, Wanhua, Farrow, Samatha, Downes, Kate, Jermutus, Lutz, Minter, Ralph, Al-Lamki, Rafia S., Pober, Jordan S., Bradley, John R.
में प्रकाशित Sci Rep (2018)

Elevated levels of tissue factor pathway inhibitor in patients with mild to moderate bleeding tendency

द्वारा Mehic, Dino, Tolios, Alexander, Hofer, Stefanie, Ay, Cihan, Haslacher, Helmuth, Rejtö, Judit, Ouwehand, Willem H., Downes, Kate, Haimel, Matthias, Pabinger, Ingrid, Gebhart, Johanna
में प्रकाशित Blood Adv (2021)

FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection

द्वारा Smyth, Deborah J., Cooper, Jason D., Howson, Joanna M.M., Clarke, Pamela, Downes, Kate, Mistry, Trupti, Stevens, Helen, Walker, Neil M., Todd, John A.
प्रकाशित 2011

A novel missense variant in SLC18A2 causes recessive brain monoamine vesicular transport disease and absent serotonin in platelets

द्वारा Padmakumar, Manisha, Jaeken, Jaak, Ramaekers, Vincent, Lagae, Lieven, Greene, Daniel, Thys, Chantal, Van Geet, Chris, BioResource, NIHR, Stirrups, Kathleen, Downes, Kate, Turro, Ernest, Freson, Kathleen
में प्रकाशित JIMD Rep (2019)

Monoallelic loss-of-function THPO variants cause heritable thrombocytopenia

द्वारा Cornish, Naomi, Aungraheeta, M. Riyaad, FitzGibbon, Lucy, Burley, Kate, Alibhai, Dominic, Collins, Janine, Greene, Daniel, Downes, Kate, Westbury, Sarah K., Turro, Ernest, Mumford, Andrew D.
में प्रकाशित Blood Adv (2020)

The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

द्वारा Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Payne, Felicity, Downes, Kate, Godfrey, Lisa M, Masters, Jennifer, Zeitels, Lauren R, Vella, Adrian, Walker, Neil M, Todd, John A
प्रकाशित 2007

How common are single gene mutations as a cause for lacunar stroke?: A targeted gene panel study

द्वारा Tan, Rhea Y.Y., Traylor, Matthew, Megy, Karyn, Duarte, Daniel, Deevi, Sri V.V., Shamardina, Olga, Mapeta, Rutendo P., Ouwehand, Willem H., Gräf, Stefan, Downes, Kate, Markus, Hugh S.
में प्रकाशित Neurology (2019)

Type 1 Diabetes-associated IL2RAvariationlowers IL-2 signaling and contributes to diminished CD4(+)CD25(+) regulatory T-cell function

द्वारा Garg, Garima, Tyler, Jennifer R, Yang, Jennie H M, Cutler, Antony J, Downes, Kate, Pekalski, Marcin, Bell, Louise, Nutland, Sarah, Peakman, Mark, Todd, John A, Wicker, Linda S, Tree, Timothy I M
प्रकाशित 2012

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes loci

द्वारा Cooper, Jason D, Smyth, Deborah J, Smiles, Adam M, Plagnol, Vincent, Walker, Neil M, Allen, James, Downes, Kate, Barrett, Jeffrey C, Healy, Barry, Mychaleckyj, Josyf C, Warram, James H, Todd, John A
प्रकाशित 2008

Curated disease‐causing genes for bleeding, thrombotic, and platelet disorders: Communication from the SSC of the ISTH

द्वारा Megy, Karyn, Downes, Kate, Simeoni, Ilenia, Bury, Loredana, Morales, Joannella, Mapeta, Rutendo, Bellissimo, Daniel B., Bray, Paul F., Goodeve, Anne C., Gresele, Paolo, Lambert, Michele, Reitsma, Pieter, Ouwehand, Willem H., Freson, Kathleen
में प्रकाशित J Thromb Haemost (2019)

Paired rRNA-depleted and polyA-selected RNA sequencing data and supporting multi-omics data from human T cells

द्वारा Chen, Li, Yang, Ruirui, Kwan, Tony, Tang, Chao, Watt, Stephen, Zhang, Yiming, Bourque, Guillaume, Ge, Bing, Downes, Kate, Frontini, Mattia, Ouwehand, Willem H., Lin, Jing-wen, Soranzo, Nicole, Pastinen, Tomi, Chen, Lu
में प्रकाशित Sci Data (2020)

Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients

द्वारा Downes, Kate, Marcovecchio, M. Loredana, Clarke, Pamela, Cooper, Jason D., Ferreira, Ricardo C., Howson, Joanna M. M., Jolley, Jennifer, Nutland, Sarah, Stevens, Helen E., Walker, Neil M., Wallace, Chris, Dunger, David B., Todd, John A.
प्रकाशित 2013

Mutational and phenotypic characterization of hereditary hemorrhagic telangiectasia

द्वारा Shovlin, Claire L., Simeoni, Ilenia, Downes, Kate, Frazer, Zoe C., Megy, Karyn, Bernabeu-Herrero, Maria E., Shurr, Abigail, Brimley, Jennifer, Patel, Dilipkumar, Kell, Loren, Stephens, Jonathan, Turbin, Isobel G., Aldred, Micheala A., Penkett, Christopher J., Ouwehand, Willem H., Jovine, Luca, Turro, Ernest
में प्रकाशित Blood (2020)

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

द्वारा Smyth, Deborah J, Plagnol, Vincent, Walker, Neil M, Cooper, Jason D, Downes, Kate, Yang, Jennie HM, Howson, Joanna MM, Stevens, Helen, McManus, Ross, Wijmenga, Cisca, Heap, Graham A., Dubois, Patrick C., Clayton, David G., Hunt, Karen A, van Heel, David A, Todd, John A
प्रकाशित 2008

IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production

द्वारा Maier, Lisa M., Lowe, Christopher E., Cooper, Jason, Downes, Kate, Anderson, David E., Severson, Christopher, Clark, Pamela M., Healy, Brian, Walker, Neil, Aubin, Cristin, Oksenberg, Jorge R., Hauser, Stephen L., Compston, Alistair, Sawcer, Stephen, De Jager, Philip L., Wicker, Linda S., Todd, John A., Hafler, David A.
प्रकाशित 2009

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

द्वारा Dendrou, Calliope A., Plagnol, Vincent, Fung, Erik, Yang, Jennie H. M., Downes, Kate, Cooper, Jason D., Nutland, Sarah, Coleman, Gillian, Himsworth, Matthew, Hardy, Matthew, Burren, Oliver, Healy, Barry, Walker, Neil M., Koch, Kerstin, Ouwehand, Willem H., Bradley, John R., Wareham, Nicholas J., Todd, John A., Wicker, Linda S.
प्रकाशित 2009