Evidence of association with type 1 diabetes in the SLC11A1 gene region

BACKGROUND: Linkage and congenic strain analyses using the nonobese diabetic (NOD) mouse as a model for human type 1 autoimmune diabetes (T1D) have identified several NOD mouse Idd (insulin dependent diabetes) loci, including Slc11a1 (formerly known as Nramp1). Genetic variants in the orthologous re...

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Autors principals: Yang, Jennie HM, Downes, Kate, Howson, Joanna MM, Nutland, Sarah, Stevens, Helen E, Walker, Neil M, Todd, John A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114708/
https://ncbi.nlm.nih.gov/pubmed/21524304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-59
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