Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct

OBJECTIVE: A major feature of type 1 diabetes is the appearance of islet autoantibodies before diagnosis. However, although the genetics of type 1 diabetes is advanced, the genetics of islet autoantibodies needs further investigation. The primary susceptibility loci in type 1 diabetes, the HLA class...

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Bibliografiske detaljer
Main Authors: Howson, Joanna M.M., Stevens, Helen, Smyth, Deborah J., Walker, Neil M., Chandler, Kyla A., Bingley, Polly J., Todd, John A.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2011
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178284/
https://ncbi.nlm.nih.gov/pubmed/21831970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0131
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