Elevated levels of tissue factor pathway inhibitor in patients with mild to moderate bleeding tendency

High levels of tissue factor pathway inhibitor (TFPI), caused by a longer TFPIα half-life after binding to a factor V splice variant and variants in the F5 gene, were recently identified in 2 families with an as-yet-unexplained bleeding tendency. This study aimed to investigate free TFPIα in a well-...

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Detalhes bibliográficos
Publicado no:Blood Adv
Principais autores: Mehic, Dino, Tolios, Alexander, Hofer, Stefanie, Ay, Cihan, Haslacher, Helmuth, Rejtö, Judit, Ouwehand, Willem H., Downes, Kate, Haimel, Matthias, Pabinger, Ingrid, Gebhart, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839354/
https://ncbi.nlm.nih.gov/pubmed/33496735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003464
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