IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production

Multiple sclerosis (MS) and type 1 diabetes (T1D) are organ-specific autoimmune disorders with significant heritability, part of which is conferred by shared alleles. For decades, the Human Leukocyte Antigen (HLA) complex was the only known susceptibility locus for both T1D and MS, but loci outside...

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Detalhes bibliográficos
Main Authors: Maier, Lisa M., Lowe, Christopher E., Cooper, Jason, Downes, Kate, Anderson, David E., Severson, Christopher, Clark, Pamela M., Healy, Brian, Walker, Neil, Aubin, Cristin, Oksenberg, Jorge R., Hauser, Stephen L., Compston, Alistair, Sawcer, Stephen, De Jager, Philip L., Wicker, Linda S., Todd, John A., Hafler, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602853/
https://ncbi.nlm.nih.gov/pubmed/19119414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000322
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