Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) with a strong genetic component. Variation in the major histocompatibility complex (MHC) on chromosome 6p21, specifically the HLA-DRB1*15 haplotype, is the strongest genetic factor for MS, yet it is estima...

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Detalhes bibliográficos
Main Authors: Barcellos, Lisa F., Ramsay, Patricia P., Caillier, Stacy J., Sawcer, Stephen, Haines, Jonathan, Schmidt, Silke, Pericak-Vance, Margaret, Compston, D. Alastair S., Gabatto, Pablo, Hauser, Stephen L., Oksenberg, Jorge R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020442/
https://ncbi.nlm.nih.gov/pubmed/18580885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2008.41
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