CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis

The MHC class II transactivator gene (CIITA) is an important transcription factor regulating gene required for HLA class II MHC-restricted antigen presentation. Association with HLA class II variation, particularly HLA-DRB1*1501, has been well-established for multiple sclerosis (MS). In addition, th...

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Main Authors: Bronson, Paola G., Caillier, Stacy, Ramsay, Patricia P., McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Hauser, Stephen L., Oksenberg, Jorge R., Barcellos, Lisa F.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Association Studies Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865376/
https://ncbi.nlm.nih.gov/pubmed/20211854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq101
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