Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12 566 individuals

The primary genetic risk factor in multiple sclerosis (MS) is the HLA-DRB1*1501 allele; however, much of the remaining genetic contribution to MS has yet to be elucidated. Several lines of evidence support a role for neuroendocrine system involvement in autoimmunity which may, in part, be geneticall...

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Autori principali: Briggs, Farren B.S., Bartlett, Selena E., Goldstein, Benjamin A., Wang, Joanne, McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Oksenberg, Jorge R., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Barcellos, Lisa F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Association Studies Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951862/
https://ncbi.nlm.nih.gov/pubmed/20699326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq328
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