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Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12 566 individuals

The primary genetic risk factor in multiple sclerosis (MS) is the HLA-DRB1*1501 allele; however, much of the remaining genetic contribution to MS has yet to be elucidated. Several lines of evidence support a role for neuroendocrine system involvement in autoimmunity which may, in part, be geneticall...

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Bibliographic Details
Main Authors: Briggs, Farren B.S., Bartlett, Selena E., Goldstein, Benjamin A., Wang, Joanne, McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Oksenberg, Jorge R., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Barcellos, Lisa F.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951862/
https://ncbi.nlm.nih.gov/pubmed/20699326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq328
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