No evidence of association of the rare nsSNP rs35667974 in IFIH1 with Multiple Sclerosis

por Bergamaschi, Laura, Ban, Maria, Leone, Maurizio A., Sawcer, Stephen J., D'Alfonso, Sandra
Publicado 2010

Effect of age at puberty on risk of multiple sclerosis: A mendelian randomization study

por Harroud, Adil, Morris, John A., Forgetta, Vincenzo, Mitchell, Ruth, Smith, George Davey, Sawcer, Stephen J., Richards, J. Brent
Publicado en Neurology (2019)

Experience from two decades of the Cambridge Rapid Access Neurology Clinic

por Axinte, Laura T, Fiddes, Barnaby D, Donaghy, Alastair, Whyte, Adam, Allen, Chris, Sawcer, Stephen J, Adam, Robert J, Stacpoole, Sybil RL
Publicado en Clin Med (Lond) (2015)

IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H)

por Jones, Joanne L., Phuah, Chia-Ling, Cox, Amanda L., Thompson, Sara A., Ban, Maria, Shawcross, Jacqueline, Walton, Amie, Sawcer, Stephen J., Compston, Alastair, Coles, Alasdair J.
Publicado 2009

Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls

por Fortune, Mary D., Guo, Hui, Burren, Oliver, Schofield, Ellen, Walker, Neil M., Ban, Maria, Sawcer, Stephen J., Bowes, John, Worthington, Jane, Barton, Ann, Eyre, Steve, Todd, John A., Wallace, Chris
Publicado en Nat Genet (2015)

Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells

por Morin, Andréanne, Kwan, Tony, Ge, Bing, Letourneau, Louis, Ban, Maria, Tandre, Karolina, Caron, Maxime, Sandling, Johanna K., Carlsson, Jonas, Bourque, Guillaume, Laprise, Catherine, Montpetit, Alexandre, Syvanen, Ann-Christine, Ronnblom, Lars, Sawcer, Stephen J., Lathrop, Mark G., Pastinen, Tomi
Publicado en BMC Med Genomics (2016)

Genetic Variation in the IL7RA/IL7 Pathway Increases Multiple Sclerosis Susceptibility

por Zuvich, Rebecca L., McCauley, Jacob L., Oksenberg, Jorge R., Sawcer, Stephen J., De Jager, Philip L., Aubin, Cristin, Cross, Anne H., Piccio, Laura, Aggarwal, Neelum T., Evans, Denis, Hafler, David A., Compston, Alastair, Hauser, Stephen L., Pericak-Vance, Margaret A., Haines, Jonathan L.
Publicado 2010

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA–CLEC16A–SOCS1 gene complex

por Zuvich, Rebecca L., Bush, William S., McCauley, Jacob L., Beecham, Ashley H., De Jager, Philip L., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Sawcer, Stephen J., Pericak-Vance, Margaret A., Barcellos, Lisa F., Mortlock, Douglas P., Haines, Jonathan L.
Publicado 2011

Variation Within DNA Repair Pathway Genes and Risk of Multiple Sclerosis

por Briggs, Farren B. S., Goldstein, Benjamin A., McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Oksenberg, Jorge R., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Barcellos, Lisa F.
Publicado 2010

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping

por Wallace, Chris, Cutler, Antony J, Pontikos, Nikolas, Pekalski, Marcin L, Burren, Oliver S, Cooper, Jason D, García, Arcadio Rubio, Ferreira, Ricardo C, Guo, Hui, Walker, Neil M, Smyth, Deborah J, Rich, Stephen S, Onengut-Gumuscu, Suna, Sawcer, Stephen J, Ban, Maria, Richardson, Sylvia, Todd, John A, Wicker, Linda S
Publicado en PLoS Genet (2015)

CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis

por Bronson, Paola G., Caillier, Stacy, Ramsay, Patricia P., McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Hauser, Stephen L., Oksenberg, Jorge R., Barcellos, Lisa F.
Publicado 2010

Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12 566 individuals

por Briggs, Farren B.S., Bartlett, Selena E., Goldstein, Benjamin A., Wang, Joanne, McCauley, Jacob L., Zuvich, Rebecca L., De Jager, Philip L., Rioux, John D., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Oksenberg, Jorge R., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L., Barcellos, Lisa F.
Publicado 2010

A Major Histocompatibility Class I Locus Contributes to Multiple Sclerosis Susceptibility Independently from HLA-DRB1*15:01

por Cree, Bruce A. C., Rioux, John D., McCauley, Jacob L., Gourraud, Pierre-Antoine F. D., Goyette, Philippe, McElroy, Joseph, De Jager, Philip, Santaniello, Adam, Vyse, Timothy J., Gregersen, Peter K., Mirel, Daniel, Hafler, David A., Haines, Jonathan L., Pericak-Vance, Margaret A., Compston, Alastair, Sawcer, Stephen J., Oksenberg, Jorge R., Hauser, Stephen L.
Publicado 2010

Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations

por Rua, Catarina, Raman, Betty, Rodgers, Christopher T, Newcombe, Virginia F J, Manktelow, Anne, Chatfield, Doris A, Sawcer, Stephen J, Outtrim, Joanne G, Lupson, Victoria C, Stamatakis, Emmanuel A, Williams, Guy B, Clarke, William T, Qiu, Lin, Ezra, Martyn, McDonald, Rory, Clare, Stuart, Cassar, Mark, Neubauer, Stefan, Ersche, Karen D, Bullmore, Edward T, Menon, David K, Pattinson, Kyle, Rowe, James B
Publicado en Brain (2024)

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

por Rioux, John D., Goyette, Philippe, Vyse, Timothy J., Hammarström, Lennart, Fernando, Michelle M. A., Green, Todd, De Jager, Philip L., Foisy, Sylvain, Wang, Joanne, de Bakker, Paul I. W., Leslie, Stephen, McVean, Gilean, Padyukov, Leonid, Alfredsson, Lars, Annese, Vito, Hafler, David A., Pan-Hammarström, Qiang, Matell, Ritva, Sawcer, Stephen J., Compston, Alastair D., Cree, Bruce A. C., Mirel, Daniel B., Daly, Mark J., Behrens, Tim W., Klareskog, Lars, Gregersen, Peter K., Oksenberg, Jorge R., Hauser, Stephen L.
Publicado 2009

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci

por McCauley, Jacob L., Zuvich, Rebecca L., Beecham, Ashley H., De Jager, Philip L., Konidari, Ioanna, Whitehead, Patrice L., Aubin, Cristin, Ban, Maria, Pobywajlo, Susan, Briskin, Rebeccah, Romano, Susan, Aggarwal, Neelum T., Piccio, Laura, McArdle, Wendy L., Strachan, David P., Evans, Denis, Cross, Anne H., Cree, Bruce, Rioux, John D., Barcellos, Lisa F., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Oksenberg, Jorge R., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L.
Publicado 2010

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis

por Goris, An, van Setten, Jessica, Diekstra, Frank, Ripke, Stephan, Patsopoulos, Nikolaos A., Sawcer, Stephen J., van Es, Michael, Andersen, Peter M., Melki, Judith, Meininger, Vincent, Hardiman, Orla, Landers, John E., Brown, Robert H., Shatunov, Aleksey, Leigh, Nigel, Al-Chalabi, Ammar, Shaw, Christopher E., Traynor, Bryan J., Chiò, Adriano, Restagno, Gabriella, Mora, Gabriele, Ophoff, Roel A., Oksenberg, Jorge R., Van Damme, Philip, Compston, Alastair, Robberecht, Wim, Dubois, Bénédicte, van den Berg, Leonard H., De Jager, Philip L., Veldink, Jan H., de Bakker, Paul I.W.
Publicado 2014

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

por De Jager, Philip L, Jia, Xiaoming, Wang, Joanne, de Bakker, Paul I W, Ottoboni, Linda, Aggarwal, Neelum T, Piccio, Laura, Raychaudhuri, Soumya, Tran, Dong, Aubin, Cristin, Briskin, Rebeccah, Romano, Susan, Baranzini, Sergio E, McCauley, Jacob L, Pericak-Vance, Margaret A, Haines, Jonathan L, Gibson, Rachel A, Naeglin, Yvonne, Uitdehaag, Bernard, Matthews, Paul M, Kappos, Ludwig, Polman, Chris, McArdle, Wendy L, Strachan, David P, Evans, Denis, Cross, Anne H, Daly, Mark J, Compston, Alastair, Sawcer, Stephen J, Weiner, Howard L, Hauser, Stephen L, Hafler, David A, Oksenberg, Jorge R
Publicado 2009

Genetic variants are major determinants of CSF antibody levels in multiple sclerosis

por Goris, An, Pauwels, Ine, Gustavsen, Marte W., van Son, Brechtje, Hilven, Kelly, Bos, Steffan D., Celius, Elisabeth Gulowsen, Berg-Hansen, Pål, Aarseth, Jan, Myhr, Kjell-Morten, D’Alfonso, Sandra, Barizzone, Nadia, Leone, Maurizio A., Martinelli Boneschi, Filippo, Sorosina, Melissa, Liberatore, Giuseppe, Kockum, Ingrid, Olsson, Tomas, Hillert, Jan, Alfredsson, Lars, Bedri, Sahl Khalid, Hemmer, Bernhard, Buck, Dorothea, Berthele, Achim, Knier, Benjamin, Biberacher, Viola, van Pesch, Vincent, Sindic, Christian, Bang Oturai, Annette, Søndergaard, Helle Bach, Sellebjerg, Finn, Jensen, Poul Erik H., Comabella, Manuel, Montalban, Xavier, Pérez-Boza, Jennifer, Malhotra, Sunny, Lechner-Scott, Jeannette, Broadley, Simon, Slee, Mark, Taylor, Bruce, Kermode, Allan G., Gourraud, Pierre-Antoine, Sawcer, Stephen J., Andreassen, Bettina Kullle, Dubois, Bénédicte, Harbo, Hanne F.
Publicado en Brain (2015)

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

por Zhou, Kaixin, Bellenguez, Celine, Spencer, Chris CA, Bennett, Amanda J, Coleman, Ruth L, Tavendale, Roger, Hawley, Simon A., Donnelly, Louise A, Schofield, Chris, Groves, Christopher J, Burch, Lindsay, Carr, Fiona, Strange, Amy, Freeman, Colin, Blackwell, Jenefer M, Bramon, Elvira, Brown, Matthew A, Casas, Juan P, Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Dronov, Serge, Duncanson, Audrey, Edkins, Sarah, Gray, Emma, Hunt, Sarah, Jankowski, Janusz, Langford, Cordelia, Markus, Hugh S, Mathew, Christopher G, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Samani, Nilesh J, Trembath, Richard, Viswanathan, Ananth C, Wood, Nicholas W, Harries, Lorna W, Hattersley, Andrew T, Doney, Alex SF, Colhoun, Helen, Morris, Andrew D, Sutherland, Calum, Hardie, D. Grahame, Peltonen, Leena, McCarthy, Mark I, Holman, Rury R., Palmer, Colin N.A., Donnelly, Peter, Pearson, Ewan R
Publicado 2010