Novel Insights Into the Etiology of Diabetes From Genome-Wide Association Studies

Por Palmer, Colin N.A.
Publicado em 2009

Ligand Modulated Antagonism of PPARγ by Genomic and Non-Genomic Actions of PPARδ

Por Gustafsson, Mattias C. U., Knight, Deborah, Palmer, Colin N. A.
Publicado em 2009

Effect of Serotonin Transporter 5HTTLPR Polymorphism on Gastrointestinal Intolerance to Metformin: A GoDARTS Study

Por Dujic, Tanja, Zhou, Kaixin, Tavendale, Roger, Palmer, Colin N.A., Pearson, Ewan R.
Publicado no Diabetes Care (2016)

Activation of PPARβ/δ Causes a Psoriasis-Like Skin Disease In Vivo

Por Romanowska, Malgorzata, Reilly, Louise, Palmer, Colin N. A., Gustafsson, Mattias C. U., Foerster, John
Publicado em 2010

PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice

Por Garbacz, Wojciech G., Huang, Jeffrey T. J., Higgins, Larry G., Wahli, Walter, Palmer, Colin N. A.
Publicado no PPAR Res (2015)

Utility of Population-Level DNA Sequence Data in the Diagnosis of Hereditary Endocrine Disease

Por Newey, Paul J., Berg, Jonathan N., Zhou, Kaixin, Palmer, Colin N.A., Thakker, Rajesh V.
Publicado no J Endocr Soc (2017)

Interaction between variants in the CYP2C9 and POR genes and the risk of sulfonylurea‐induced hypoglycaemia: A GoDARTS Study

Por Dujic, Tanja, Zhou, Kaixin, Donnelly, Louise A., Leese, Graham, Palmer, Colin N. A., Pearson, Ewan R.
Publicado no Diabetes Obes Metab (2017)

Investigating Real‐World Clopidogrel Pharmacogenetics in Stroke Using a Bioresource Linked to Electronic Medical Records

Por Tornio, Aleksi, Flynn, Rob, Morant, Steve, Velten, Elena, Palmer, Colin N. A., MacDonald, Thomas M., Doney, Alex S. F.
Publicado no Clin Pharmacol Ther (2017)

A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain

Por Meng, Weihua, Deshmukh, Harshal A., Donnelly, Louise A., Torrance, Nicola, Colhoun, Helen M., Palmer, Colin N.A., Smith, Blair H.
Publicado no EBioMedicine (2015)

Glycemic Exposure and Blood Pressure Influencing Progression and Remission of Diabetic Retinopathy: A longitudinal cohort study in GoDARTS

Por Liu, Yiyuan, Wang, Minghui, Morris, Andrew D., Doney, Alex S.F., Leese, Graham P., Pearson, Ewan R., Palmer, Colin N.A.
Publicado em 2013

A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract

Por Chang, Cheng, Zhang, Kaida, Veluchamy, Abirami, Hébert, Harry L., Looker, Helen C., Colhoun, Helen M., Palmer, Colin N. A., Meng, Weihua
Publicado no Invest Ophthalmol Vis Sci (2016)

PheGWAS: a new dimension to visualize GWAS across multiple phenotypes

Por George, Gittu, Gan, Sushrima, Huang, Yu, Appleby, Philip, Nar, A S, Venkatesan, Radha, Mohan, Viswanathan, Palmer, Colin N A, Doney, Alex S F
Publicado no Bioinformatics (2020)

Efficacy of Modern Diabetes Treatments DPP-4i, SGLT-2i, and GLP-1RA in White and Asian Patients With Diabetes: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Por Gan, Sushrima, Dawed, Adem Y., Donnelly, Louise A., Nair, Anand T.N., Palmer, Colin N.A., Mohan, Viswanathan, Pearson, Ewan R.
Publicado no Diabetes Care (2020)

Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo

Por Higgins, Larry G., Garbacz, Wojciech G., Gustafsson, Mattias C. U., Nainamalai, Sitheswaran, Ashby, Peter R., Wolf, C. Roland, Palmer, Colin N. A.
Publicado em 2012

Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk

Por Lango, Hana, Palmer, Colin N.A., Morris, Andrew D., Zeggini, Eleftheria, Hattersley, Andrew T., McCarthy, Mark I., Frayling, Timothy M., Weedon, Michael N.
Publicado em 2008

How can we optimise inhaled beta2 agonist dose as ‘reliever’ medicine for wheezy pre-school children? Study protocol for a randomised controlled trial

Por Mukhopadhyay, Somnath, Seddon, Paul, Earl, Gemma, Wileman, Emma, Symes, Liz, Olden, Cathy, Alberti, Corinne, Bremner, Stephen, Lansley, Alison, Palmer, Colin N. A., Beydon, Nicole
Publicado no Trials (2016)

The impact of phenotype, ethnicity and genotype on progression of type 2 diabetes mellitus

Por Thakarakkattil Narayanan Nair, Anand, Donnelly, Louise A., Dawed, Adem Y., Gan, Sushrima, Anjana, Ranjit M., Viswanathan, Mohan, Palmer, Colin N. A., Pearson, Ewan R.
Publicado no Endocrinol Diabetes Metab (2020)

Combined Effect of Inflammatory Gene Polymorphisms and the Risk of Ischemic Stroke in a Prospective Cohort of Subjects With Type 2 Diabetes: A Go-DARTS Study

Por Palmer, Colin N.A., Kimber, Charlotte H., Doney, Alex S.F., Proia, Anna S., Morris, Andrew D., Gaetani, Eleonora, Quarta, Miriam, Smith, Roy C., Pola, Roberto
Publicado em 2010

Cohort profile: the Scottish Research register SHARE. A register of people interested in research participation linked to NHS data sets

Por McKinstry, Brian, Sullivan, Frank M, Vasishta, Shobna, Armstrong, Roma, Hanley, Janet, Haughney, John, Philip, Sam, Smith, Blair H, Wood, Amanda, Palmer, Colin N A
Publicado no BMJ Open (2017)

Genetic correlations between pain phenotypes and depression and neuroticism

Por Meng, Weihua, Adams, Mark J., Reel, Parminder, Rajendrakumar, Aravind, Huang, Yu, Deary, Ian J., Palmer, Colin N. A., McIntosh, Andrew M., Smith, Blair H.
Publicado no Eur J Hum Genet (2019)