PheGWAS: a new dimension to visualize GWAS across multiple phenotypes

MOTIVATION: PheGWAS was developed to enhance exploration of phenome-wide pleiotropy at the genome-wide level through the efficient generation of a dynamic visualization combining Manhattan plots from GWAS with PheWAS to create a 3D ‘landscape’. Pleiotropy in sub-surface GWAS significance strata can...

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Vydáno v:Bioinformatics
Hlavní autoři: George, Gittu, Gan, Sushrima, Huang, Yu, Appleby, Philip, Nar, A S, Venkatesan, Radha, Mohan, Viswanathan, Palmer, Colin N A, Doney, Alex S F
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Original Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178436/
https://ncbi.nlm.nih.gov/pubmed/31860083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz944
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