Implications of intercorrelation between hepatic CYP3A4‐CYP2C8 enzymes for the evaluation of drug–drug interactions: a case study with repaglinide

Por Doki, Kosuke, Darwich, Adam S., Achour, Brahim, Tornio, Aleksi, Backman, Janne T., Rostami‐Hodjegan, Amin
Publicado no Br J Clin Pharmacol (2018)

Effect of grapefruit juice on the bioactivation of prasugrel

Por Holmberg, Mikko T, Tornio, Aleksi, Hyvärinen, Hanna, Neuvonen, Mikko, Neuvonen, Pertti J, Backman, Janne T, Niemi, Mikko
Publicado no Br J Clin Pharmacol (2015)

Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril

Por Tarkiainen, E Katriina, Tornio, Aleksi, Holmberg, Mikko T, Launiainen, Terhi, Neuvonen, Pertti J, Backman, Janne T, Niemi, Mikko
Publicado no Br J Clin Pharmacol (2015)

Grapefruit juice markedly increases the plasma concentrations and antiplatelet effects of ticagrelor in healthy subjects

Por Holmberg, Mikko T, Tornio, Aleksi, Joutsi-Korhonen, Lotta, Neuvonen, Mikko, Neuvonen, Pertti J, Lassila, Riitta, Niemi, Mikko, Backman, Janne T
Publicado em 2013

Investigating Real‐World Clopidogrel Pharmacogenetics in Stroke Using a Bioresource Linked to Electronic Medical Records

Por Tornio, Aleksi, Flynn, Rob, Morant, Steve, Velten, Elena, Palmer, Colin N. A., MacDonald, Thomas M., Doney, Alex S. F.
Publicado no Clin Pharmacol Ther (2017)

Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics

Por Hirvensalo, Päivi, Tornio, Aleksi, Neuvonen, Mikko, Tapaninen, Tuija, Paile‐Hyvärinen, Maria, Kärjä, Vesa, Männistö, Ville T., Pihlajamäki, Jussi, Backman, Janne T., Niemi, Mikko
Publicado no Clin Pharmacol Ther (2017)

A common missense variant of LILRB5 is associated with statin intolerance and myalgia

Por K Siddiqui, Moneeza, Maroteau, Cyrielle, Veluchamy, Abirami, Tornio, Aleksi, Tavendale, Roger, Carr, Fiona, Abelega, Ngu-Uma, Carr, Dan, Bloch, Katyrzyna, Hallberg, Par, Yue, Qun-Ying, Pearson, Ewan R, Colhoun, Helen M, Morris, Andrew D, Dow, Eleanor, George, Jacob, Pirmohamed, Munir, Ridker, Paul M, Doney, Alex S F, Alfirevic, Ana, Wadelius, Mia, Maitland-van der Zee, Anke-Hilse, Chasman, Daniel I, Palmer, Colin N A
Publicado no Eur Heart J (2017)