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Interaction between variants in the CYP2C9 and POR genes and the risk of sulfonylurea‐induced hypoglycaemia: A GoDARTS Study

Data on the association of CYP2C9 genetic polymorphisms with sulfonylurea (SU)‐induced hypoglycaemia (SH) are inconsistent. Recent studies showed that variants in the P450 oxidoreductase (POR) gene could affect CYP2C9 activity. In this study, we explored the effects of POR*28 and combined CYP2C9*2 a...

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Библиографические подробности
Опубликовано в: :Diabetes Obes Metab
Главные авторы: Dujic, Tanja, Zhou, Kaixin, Donnelly, Louise A., Leese, Graham, Palmer, Colin N. A., Pearson, Ewan R.
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724509/
https://ncbi.nlm.nih.gov/pubmed/28656666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13046
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