Interaction between variants in the CYP2C9 and POR genes and the risk of sulfonylurea‐induced hypoglycaemia: A GoDARTS Study

Data on the association of CYP2C9 genetic polymorphisms with sulfonylurea (SU)‐induced hypoglycaemia (SH) are inconsistent. Recent studies showed that variants in the P450 oxidoreductase (POR) gene could affect CYP2C9 activity. In this study, we explored the effects of POR*28 and combined CYP2C9*2 a...

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Bibliographic Details
Published in:Diabetes Obes Metab
Main Authors: Dujic, Tanja, Zhou, Kaixin, Donnelly, Louise A., Leese, Graham, Palmer, Colin N. A., Pearson, Ewan R.
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2017
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Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724509/
https://ncbi.nlm.nih.gov/pubmed/28656666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13046
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